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the selective expression of FZD10 in brain vascular endothelial cells points at a potential role of FZD10-Galpha13 (show GNA13 Proteins) signalling in central nervous system angiogenesis.
there was a strong inverse correlation between nuclear immunostaining scores for beta-catenin (show CTNNB1 Proteins) expression and expression patterns of FZD10
FZD10 transactivation causes the activation of the Dvl (show DVL2 Proteins)-Rac1-JNK (show MAPK8 Proteins) pathway and is associated with the development/progression of synovial sarcomas
Data demonstrate that Wnt7b (show WNT7B Proteins) signals through Fzd1 (show Fzd1 Proteins) and -10 and LRP5 (show LRP5 Proteins) and implicate these Wnt (show WNT2 Proteins) coreceptors in the regulation of lung airway and vascular development.
Interprets Wnt (show WNT2 Proteins) signals during embryonic mesoderm and neural induction.
Frizzled10 expression is very strong during embryonic development of the CNS and may play an essential role in spatial and temporal regulation during neural development.
Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development.
Results suggest that Frizzed 10 mediates Wnt1 (show WNT1 Proteins) signalling to determine sensory neural differentiation in Xenopus in vivo and in mouse cell culture.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
frizzled 10, seven transmembrane spanning receptor
, frizzled homolog 10
, seven transmembrane spanning receptor
, frizzled homolog 4
, frizzled homolog B
, Drosophila polarity gene (frizzled) homologue
, Drosophila polarity gene homolog 2
, frizzled 10B
, frizzled 9
, frizzled family receptor 10