FZD10 Protein

Catalog No. ABIN7491645

Product Details

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Protein Type: Synthetic

Origin: Human

Source: HEK-293 Cells

Purpose: Human FZD10 full length protein-synthetic nanodisc

Characteristics: Full Length Transmembrane Proteins (synthetic Nanodisc)

Application Details

Application Notes:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Comment:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Alternative Name: FZD10 (FZD10 Products)

Synonyms: CD350 Protein, FZ-10 Protein, Fz10 Protein, FzE7 Protein, hFz10 Protein, cFz-10 Protein, Fz-10 Protein, Xfr9 Protein, Xfz10 Protein, frizzled-10 Protein, frizzled10 Protein, fz10 Protein, fze7 Protein, hfz10 Protein, fk48e04 Protein, fz4 Protein, fzb Protein, wu:fk48e04 Protein, zg04 Protein, Xfz10A Protein, fzd10a Protein, Xfz10B Protein, Xfz9 Protein, fzd10b Protein, fzd9 Protein, frizzled class receptor 10 Protein, frizzled class receptor 10 L homeolog Protein, frizzled class receptor 10 S homeolog Protein, FZD10 Protein, fzd10 Protein, Fzd10 Protein, fzd10.L Protein, fzd10.S Protein

Background: CD350, FZ-10, Fz10, FzE7, hFz10
Description: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]

Molecular Weight: The human full length FZD10 protein has a MW of 65.2 kDa

UniProt: Q9ULW2

Pathways: WNT Signaling