FZD10 Protein (AA 21-161) (His tag)

Catalog No. ABIN7013531

Product Details

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Protein Type: Recombinant

Protein Characteristics: AA 21-161

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FZD10 protein is labelled with His tag.

Characteristics: Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified)

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: MALS verified

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: FZD10 (Frizzled Family Receptor 10 (FZD10))

Alternative Name: Frizzled-10 (FZD10 Products)

Synonyms: CD350 Protein, FZ-10 Protein, Fz10 Protein, FzE7 Protein, hFz10 Protein, cFz-10 Protein, Fz-10 Protein, Xfr9 Protein, Xfz10 Protein, frizzled-10 Protein, frizzled10 Protein, fz10 Protein, fze7 Protein, hfz10 Protein, fk48e04 Protein, fz4 Protein, fzb Protein, wu:fk48e04 Protein, zg04 Protein, Xfz10A Protein, fzd10a Protein, Xfz10B Protein, Xfz9 Protein, fzd10b Protein, fzd9 Protein, frizzled class receptor 10 Protein, frizzled class receptor 10 L homeolog Protein, frizzled class receptor 10 S homeolog Protein, FZD10 Protein, fzd10 Protein, Fzd10 Protein, fzd10.L Protein, fzd10.S Protein

Background: Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.

Molecular Weight: 18.0 kDa

NCBI Accession: NP_009128

Pathways: WNT Signaling