ZNF384 Proteins

(Zinc Finger Protein 384 (ZNF384))

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011].

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ZNF384 Protein (AA 1-577) (His tag)

custom-made ZNF384 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant ZNF384 Protein, UniprotID Q8TF68

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Catalog No. ABIN7545268

Details

ZNF384 Protein (AA 307-540) (His tag)

ZNF384 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

Catalog No. ABIN7415959

Details

ZNF384 Protein (AA 1-577) (Strep Tag)

custom-made ZNF384 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3075719