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15 KDa Selenoprotein Proteins (SEP15)

SEP15 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Additionally we are shipping 15 KDa Selenoprotein Antibodies (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEP15 9403 O60613
SEP15 93684 Q9ERR7
Rat SEP15 SEP15 113922 Q923V8
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Top 15 KDa Selenoprotein Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details

SEP15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for 15 KDa Selenoprotein (SEP15) Interaction Partners

Human 15 KDa Selenoprotein (SEP15) interaction partners

  1. Results suggest that SEP15 plays important roles in the regulation of the G1 phase during the cell cycle as well as in cell motility of Chang liver cells offering a novel functional link between the cell cycle and cell motility.

  2. Sep15 in Chang liver cells regulates the pathway that antagonizes RhoA/ROCK/MLC-dependent non-apoptotic bleb formation.

  3. This study provides evidence that SEP15 genetic variation may influence prostate cancer mortality

  4. SEP15, encoding a 15-kDa selenium-containing protein was shown to be downregulated in approximately 60% of MM cell lines and tumor specimens. A SEP15 polymorphic variant, 1125A, resides in the SECIS recognition element

  5. It appears that those with the Sep15 1125 AA genotype may benefit most from a higher Se intake, whereas in those with the GG or GA genotype, a higher Se status may increase the risk for lung cancer.

  6. Studies in mouse show that Sep15 may have redox function.

Mouse (Murine) 15 KDa Selenoprotein (SEP15) interaction partners

  1. Considering the variable expression levels of Sep15 and TR1 found within the human population, our results provide insights into new roles of selenoproteins in cancer

  2. Cataracts resulted from an improper folding status of lens proteins caused by Sep15 deficiency.

  3. These data suggest tissue specificity in the cancer-protective effects of Sep15 downregulation, which are mediated, at least in part, by influencing the cell cycle.

  4. Transfecting Sep15 gene did not influence the growth characteristics of BEL (show LHX2 Proteins)-7402 cell line and Sep15 may have redox function.

  5. The cysteine-rich domain of Sep15 exclusively mediates protein-protein interactions with UDP-glucose:glycoprotein glucosyltransferase.

15 KDa Selenoprotein (SEP15) Protein Profile

Protein Summary

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with 15 KDa Selenoprotein Proteins (SEP15)

  • 15 kDa selenoprotein (SEP15)
  • selenoprotein (Sep15)
  • selenoprotein 15 (sep15)
  • selenoprotein 15 (Sep15)
  • 9430015P09Rik protein
  • cb29 protein
  • zgc:86882 protein

Protein level used designations for 15 KDa Selenoprotein Proteins (SEP15)

15kDa selenoprotein , 15 kDa selenoprotein , 15-kDa selenoprotein

GENE ID SPECIES
9403 Homo sapiens
612493 Canis lupus familiaris
100038009 Sus scrofa
614360 Bos taurus
93684 Mus musculus
352923 Danio rerio
113922 Rattus norvegicus
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