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3-Ketodihydrosphingosine Reductase Proteins (KDSR)

The protein encoded by KDSR catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. Additionally we are shipping FVT1 Antibodies (38) and FVT1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KDSR 2531 Q06136
KDSR 70750 Q6GV12
Rat KDSR KDSR 360833  
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Top FVT1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human His tag   5 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

KDSR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

Top referenced FVT1 Proteins

  1. Human FVT1 Protein expressed in Escherichia coli (E. coli) - ABIN667376 : Kihara, Igarashi: FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN667376

More Proteins for 3-Ketodihydrosphingosine Reductase (KDSR) Interaction Partners

Human 3-Ketodihydrosphingosine Reductase (KDSR) interaction partners

  1. FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane

  2. Data show that mutations in FVT1 do not contribute significantly to the cause of motor neuron diseases in the human population.

  3. FVT1 is significantly underexpressed by germinal center-type diffuse large B-cell lymphoma compared with non-germinal center-type DLBCL, follicular lymphoma, & normal tonsil control samples. Increased expression of FVT1 correlated with decreased survival.

  4. Describes an Ala-175 to Thr mutation in the bovine ortholog that causes spinal muscular atrophy. This residue is conserved in several species, including human.

Mouse (Murine) 3-Ketodihydrosphingosine Reductase (KDSR) interaction partners

  1. FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane

Cow (Bovine) 3-Ketodihydrosphingosine Reductase (KDSR) interaction partners

  1. G-to-A missense mutation in FVT1, encoding 3-ketodihydrosphingosine reductase, is a strong candidate for causality of spinal muscular atrophy in cattle.

FVT1 (KDSR) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.

Gene names and symbols associated with KDSR

  • 3-ketodihydrosphingosine reductase (kdsr)
  • 3-ketodihydrosphingosine reductase (KDSR)
  • 3-ketodihydrosphingosine reductase (Kdsr)
  • 6330410P18Rik protein
  • 9430079B08Rik protein
  • DHSR protein
  • Fvt1 protein
  • SDR35C1 protein
  • zgc:55947 protein

Protein level used designations for KDSR

follicular lymphoma variant translocation 1 , 3-dehydrosphinganine reductase , FVT-1 , KDS reductase , follicular variant translocation protein 1 , short chain dehydrogenase/reductase family 35C, member 1 , follicular variant translocation protein 1 homolog

GENE ID SPECIES
394114 Danio rerio
420902 Gallus gallus
738461 Pan troglodytes
100227804 Taeniopygia guttata
2531 Homo sapiens
70750 Mus musculus
360833 Rattus norvegicus
505558 Bos taurus
609655 Canis lupus familiaris
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