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3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. Additionally we are shipping HAAO Proteins (13) and HAAO Kits (6) and many more products for this protein.
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Human Polyclonal HAAO Primary Antibody for EIA, IHC (p) - ABIN499940
Huang, Jansen, Fabbri, Potter, Liyanarachchi, Chan, Liu, Crijns, Brown, Nephew, van der Zee, Cohn, Yan, Huang, Lin: Identification of candidate epigenetic biomarkers for ovarian cancer detection. in Oncology reports 2009
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Cow (Bovine) Polyclonal HAAO Primary Antibody for WB - ABIN2775371
Kim, Lee, Jeon, Oh, Jeong, Song, Kim, Lee, Kim: Identification of genes related to Parkinson's disease using expressed sequence tags. in DNA research : an international journal for rapid publication of reports on genes and genomes 2007
Methylation status of CIDEA (show CIDEA Antibodies), HAAO and RXFP3 (show RXFP3 Antibodies) had significant association with microsatellite instability in endometrial tumors.
GTF2A1 (show GTF2A1 Antibodies) alone, or GTF2A1 (show GTF2A1 Antibodies) plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer
Data show that 3-hydroxyanthranilate 3,4-dioxygenase is a monomer, characterized by the so-called cupin fold.
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
, 3-hydroxyanthranilate oxygenase
, 3-hydroxyanthranilic acid dioxygenase