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anti-5'-Nucleotidase, Cytosolic II (NT5C2) Antibodies

NT5C2 encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. Additionally we are shipping 5'-Nucleotidase, Cytosolic II Proteins (9) and 5'-Nucleotidase, Cytosolic II Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NT5C2 100363253  
NT5C2 22978 P49902
NT5C2 76952 Q3V1L4
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Top anti-5'-Nucleotidase, Cytosolic II Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in WiDr cell line lysates (35ug/lane) using NT5C... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas tissue labeled with ... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated WB NT5C2 Antibody (N-term) (ABIN656169) western blot analysis in WiDr cel... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 ug whole cell lysate) A:H1299 B:HeLa S3, 7.5% SDS P... WB Image Sample (50 ug of whole cell lysate) A: mouse liver 7.5% SDS P... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to NT5C2 on formalin-fixed par... Western Blot analysis of NT5C2 expression in transfected 293T cell lin... 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of NT5C2 expression in transfected 293T cell lin... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details

NT5C2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) , , , ,

Human , , , ,
,
Mouse (Murine) , , , ,

Top referenced anti-5'-Nucleotidase, Cytosolic II Antibodies

  1. Human Monoclonal NT5C2 Primary Antibody for IF, IHC (p) - ABIN524900 : Kulkarni, Karlsson, Szekeres, Chibalin, Krook, Zierath: Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle. in The Journal of biological chemistry 2011 (PubMed)
    Show all 4 references for ABIN524900

  2. Human Polyclonal NT5C2 Primary Antibody for EIA, WB - ABIN953765 : Niu, Zhang, Ji, Gu, Gao, Zhu: Confirmation of top polymorphisms in hypertension genome wide association study among Han Chinese. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 3 references for ABIN953765

  3. Human Polyclonal NT5C2 Primary Antibody for EIA, IHC (fro) - ABIN492874 : Galmarini, Jordheim, Dumontet: Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies. in Leukemia & lymphoma 2003 (PubMed)
    Show all 3 references for ABIN492874

  4. Human Polyclonal NT5C2 Primary Antibody for WB - ABIN493225 : Bretonnet, Jordheim, Dumontet, Lancelin: Regulation and activity of cytosolic 5'-nucleotidase II. A bifunctional allosteric enzyme of the Haloacid Dehalogenase superfamily involved in cellular metabolism. in FEBS letters 2005 (PubMed)
    Show all 3 references for ABIN493225

  5. Human Polyclonal NT5C2 Primary Antibody for IF (p), IHC (p) - ABIN739353 : Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells. in Neuroscience 2012 (PubMed)

More Antibodies against 5'-Nucleotidase, Cytosolic II Interaction Partners

Human 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. cN-II co-immunoprecipitated both with wild type Ipaf (show NLRC4 Antibodies) and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf (show NLRC4 Antibodies) lacking the LRR domain.

  2. Data indicate that type II cytosolic 5'-nucleotidase (show NT5E Antibodies) (cN-II) exerts a role in nucleotide and drug metabolism and regulating cell survival.

  3. Four novel body mass index-associated loci near the KCNQ1 (show KCNQ1 Antibodies)(rs2237892), ALDH2 (show ALDH2 Antibodies)/MYL2 (show MYL2 Antibodies) (rs671, rs12229654), ITIH4 (show ITIH4 Antibodies) (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations.

  4. These results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in acute lymphoblastic leukemia

  5. results highlight the prominent role of relapse-specific mutations in NT5C2 as a mechanism of resistance to 6-Mercaptopurine and a genetic driver of relapse in acute lymphoblastic leukemia

  6. analysis of Drosophila and human 7-methyl GMP-specific nucleotidases

  7. Polymorphisms in the CYP17A1 (show CYP17A1 Antibodies) and NT5C2 genes influence a reduction in both visceral and subcutaneous fat mass in Japanese women.

  8. seven high-resolution structures of human cN-II, including a ligand-free form and complexes with various substrates and effectors, were presented.

  9. cN-II has a role in protecting against progression of non-small cell lung cancer

  10. the expression level of cN-II mRNA might be a prognostic factor of high-risk MDS (show PAFAH1B1 Antibodies).

Cow (Bovine) 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. mutated three residues that mediate interaction in the first activation site (R144, N154, I152) and three in the second (F127, M436 and H428), and found that ApA and ADP interact with the same site, but the sites for ATP and BPG remain uncertain

5'-Nucleotidase, Cytosolic II (NT5C2) Antigen Profile

Protein Summary

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides.

Gene names and symbols associated with NT5C2

  • 5'-nucleotidase, cytosolic IIa (nt5c2a) antibody
  • 5'-nucleotidase, cytosolic II (NT5C2) antibody
  • 5'-nucleotidase, cytosolic II (nt5c2) antibody
  • 5'-nucleotidase, cytosolic II (surE2) antibody
  • 5'-nucleotidase, cytosolic II (LOC100363253) antibody
  • 5'-nucleotidase, cytosolic II (Nt5c2) antibody
  • 2010002I23Rik antibody
  • cN-II antibody
  • CnII antibody
  • ENSMUSG00000025039 antibody
  • Gm9751 antibody
  • Gmp antibody
  • Nt5b antibody
  • NT5C2 antibody
  • Pnt5 antibody
  • wu:fc36f11 antibody
  • wu:fc45b10 antibody

Protein level used designations for NT5C2

5'-nucleotidase, cytosolic II , fc36f11 , cytosolic 5'-nucleotidase II , cytosolic purine 5'-nucleotidase , cytosolic purine 5'-nucleotidase-like , 5'-nucleotidase (purine), cytosolic type B , IMP-specific 5'-NT , purine 5' nucleotidase , 5'-nucleotidase cytosolic II , cytosolic IMP/GMP-specific 5'-nucleotidase

GENE ID SPECIES
324845 Danio rerio
450706 Pan troglodytes
548490 Xenopus (Silurana) tropicalis
714292 Macaca mulatta
5808749 Sorangium cellulosum So ce56
100172749 Pongo abelii
100363253 Rattus norvegicus
100402763 Callithrix jacchus
22978 Homo sapiens
76952 Mus musculus
294016 Rattus norvegicus
477809 Canis lupus familiaris
281951 Bos taurus
423871 Gallus gallus
444729 Xenopus laevis
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