Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Synthesis and degradation of fructose 2,6-bisphosphate.. Additionally we are shipping PFKFB4 Proteins (8) and many more products for this protein.
Showing 10 out of 34 products:
Human Polyclonal PFKFB4 Primary Antibody for IHC (p), WB - ABIN392786
Blum, Jacob-Hirsch, Amariglio, Rechavi, Kloog: Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. in Cancer research 2005
Show all 4 Pubmed References
High PFKFB4 expression is associated with colon and lung cancer.
This work has uncovered a novel function of the enzymes PFKFB3 (show PFKFB3 Antibodies) and PFKFB4 in ovarian cancer cells during mitotic arrest
HIF-1alpha (show HIF1A Antibodies) transactivates hypoxia-responsive elements (HRE)-D of the promoter region of PFKFB4 in hypoxia condition.
The expression of PFKFB3 (show PFKFB3 Antibodies), PFKFB4, NAMPT (show NAMPT Antibodies), and TSPAN13 (show TSPAN13 Antibodies) is strongly up-regulated in pediatric glioma.
Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.
PFKFB4 suppresses oxidative stress and p62 (show GTF2H1 Antibodies) accumulation, without which autophagy is stimulated likely as a ROS (show ROS1 Antibodies) detoxification response.
Data indicate that the PFKFB4 expressed in multiple transformed cells and tumors functions to synthesize F2,6BP.
we found that the glycolytic enzyme PFKFB4 is essential for prostate cancer cell survival by maintaining the balance between the use of glucose for energy generation and the synthesis of antioxidants.
PFKFB4 has an important role in the progression of non-muscle-invasive bladder cancer (
PFKFB4 and HO-2 (show HMOX2 Antibodies) are expressed in a coordinated manner to maintain glucose homeostasis.
Synthesis and degradation of fructose 2,6-bisphosphate.
, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4-like
, 6PF-2-K/Fru-2,6-P2ase 4
, 6PF-2-K/Fru-2,6-P2ase testis-type isozyme
, PFK/FBPase 4
, bifunctional enzyme with kinase and biphosphatase activities
, 6PF-2-K/Fru-2,6-P2ASE testis-type isozyme