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ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 Proteins (ADAMTS1)

ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS1 Antibodies (110) and ADAMTS1 Kits (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADAMTS1 11504 P97857
ADAMTS1 9510 Q9UHI8
ADAMTS1 79252  
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Top ADAMTS1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Human His tag 5 μg Log in to see 5 to 6 Days
$194.43
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,086.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$841.86
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

ADAMTS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus) ,

More Proteins for ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. TS5 protein functions to suppress glucose uptake in adipose-derived stromal cells and thereby inhibits the synthesis, and promotes the intracellular degradation of Acan (show ACAN Proteins) and Vcan (show Vcan Proteins) by an ADAMTS other than TS5.

  2. Data suggest that ADAMTS-5 (show ADAMTS5 Proteins) oligomerization is required for full aggrecanase (show ADAMTS4 Proteins) activity in vitro and in situ (as seen in knee joint of mouse model of inflammatory arthritis); thus, blocking oligomerization inhibits ADAMTS-5 (show ADAMTS5 Proteins) activity.

  3. The resilience of casp1 (show CASP1 Proteins)(-/-) mice to SIRS lethality is associated with a lower inflammatory response, loss of hippocampal gene coexpression patterns, and increased hippocampal Adamts1 gene expression.

  4. Adamts-1 upregulation by inducers of pathological vascular remodeling is mediated by specific signal transduction pathways involving NFAT (show NFATC1 Proteins) or C/EBPbeta (show CEBPB Proteins) transcription factors.

  5. aggrecan (show ACAN Proteins) and brevican (show BCAN Proteins) proteolysis is compensated in Adamts4 (show ADAMTS4 Proteins)-/- or Adamts5 (show ADAMTS5 Proteins)-/- mice by ADAMTS proteoglycanase (show MMP3 Proteins) family members but a threshold of versican (show Vcan Proteins) proteolysis is sensitive to the loss of a single ADAMTS proteoglycanase (show MMP3 Proteins) during spinal cord injury

  6. The present study reveals ADAMT-5 expression by mast cells(MCs (show SMCP Proteins)) and that MC activation regulates the expression of the protease, thus implicating the ADAMT-5 of protease in MC function.

  7. Western blot analyses indicated that aggrecanase (show ADAMTS4 Proteins)-generated proteoglycan (show Vcan Proteins) fragments are produced after SCI.

  8. RelA/p65 (show NFkBP65 Proteins) is a potent transcriptional activator of ADAMTS5 (show ADAMTS5 Proteins) in chondrocytes during osteoarthritis development.

  9. Repair of biomechanically compromised tendons exhibiting midsubstance chondroid accumulation requires ADAMTS5 (show ADAMTS5 Proteins).

  10. this study identified, for the first time, several genes that have an ADAMTS-5 (show ADAMTS5 Proteins)-independent role in osteoarthritis(OA), identifying them as possible OA initiation candidates.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. progesterone acts via the progesterone receptor (show PGR Proteins) to modulate ADAMTS 1 and 4 levels in ovarian cancer cell lines.

  2. Data suggest that the rs416905 and rs402007 single nucleotide polymorphisms of the a disintegrin and metallo-proteinase with thrombospondin type 1 motifs (ADAMTS-1) gene may be associated with ischemic stroke caused by large artery atherosclerosis (LAA).

  3. Results show that ADAMTS1 expression is negatively regulated in breast neoplasm cells due to mir-365 targeting its 3'UTR.

  4. The aberrant methylation of ADAMTS1 may be involved in the development and progression of gastric cancer.

  5. Ectopic expression of SP1 (show PSG1 Proteins) and USF transcription factors resulted in the decrease in ADAMTS1 transcriptional activity of all promoter constructs

  6. single-nucleotide missense mutation in the ADAMTS1 gene (c. 742I>T) was found to segregate in the family, given that the affected individuals must be heterozygous for the mutation

  7. Data show that ADAMTS1 was expressed at a significantly higher level in extravillous trophoblast cells (EVTs) than in villous trophoblast cells (VTs), while both ADAM10 (show ADAM10 Proteins) and ADAM12 (show ADAM12 Proteins) were expressed at significantly higher levels in VTs than in EVTs.

  8. Dysregulated expression of ADAMTS-1 in polycystic ovary syndrome may influence oocyte quality-via Granulosa cells-oocyte paracrine and endocrine mechanism.

  9. ADAMTS1 formed a complex with VEGFC (show VEGFC Proteins), attenuated VEGFR3 (show FLT4 Proteins) phosphorylation and inhibited lymphangiogenesis in vitro.

  10. We have demonstrated that the expression of ADAMTS-1, -4 and -5 is induced during the differentiation of monocytes into macrophages.

Pig (Porcine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. Expression and induction of ADAMTS-1 through receptor-mediated action of progesterone in cumulus cells is one of essential requirements for gonadotropin-regulated cumulus expansion of porcine cumulus-oocyte complexes.

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. study indicates that disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) participates in bovine endometrial remodeling

  2. Data indicate that ADAMTS1 promoter activity and mRNA expression were increased by forskolin and human chorionic gonadotropin.

ADAMTS1 Protein Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Gene names and symbols associated with ADAMTS1

  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (adamts1)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (Adamts1)
  • 9530092O11Rik protein
  • ADAM-TS1 protein
  • ADAM-TS5 protein
  • ADAMTS protein
  • ADAMTS-1 protein
  • ADAMTS1 protein
  • ADAMTS11 protein
  • AI481094 protein
  • ASMP-2 protein
  • C3-C5 protein
  • METH-1 protein
  • METH1 protein
  • xadamts1 protein

Protein level used designations for ADAMTS1

metalloproteinase with thrombospondin-like motifs-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 1 , A disintegrin and metalloproteinase with thrombospondin motifs 1 , ADAM-TS 1 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 , A disintegrin and metalloproteinase with thrombospondin motifs 5 , ADAM-TS 5 , ADAMTS-5 , ADMP-2 , aggrecanase-2 , implantin , ADAM-TS1 , ADAMTS-1 , METH-1 , human metalloproteinase with thrombospondin type 1 motifs , a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1) , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 , a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1

GENE ID SPECIES
791251 Equus caballus
565145 Danio rerio
100548786 Meleagris gallopavo
100151734 Xenopus (Silurana) tropicalis
11504 Mus musculus
23794 Mus musculus
9510 Homo sapiens
418479 Gallus gallus
497061 Sus scrofa
512171 Bos taurus
79252 Rattus norvegicus
100415773 Ovis aries
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