ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 Proteins (ADAMTS1)

ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS1 Antibodies (119) and ADAMTS1 Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADAMTS1 11504 P97857
ADAMTS1 9510 Q9UHI8
ADAMTS1 79252  
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Top ADAMTS1 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag 5 μg Log in to see 6 to 7 Days
$194.43
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$608.00
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,086.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 15 to 18 Days
$672.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$804.38
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days
$873.13
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$873.13
Details

ADAMTS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , ,
,
Rat (Rattus) ,

More Proteins for ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. Genetic haploinsufficiency of Adamts1 in mice caus (show NOS2 Proteins)es thoracic aortic aneurysms and dissections similar to Marfan syndrome.

  2. An ADAMTS1 blocking antibody suppressed the SPARC (show SPARC Proteins)-induced collagen I secretion, indicating that SPARC (show SPARC Proteins) promoted collagen production directly through ADAMTS1 interaction. In conclusion, ADAMTS1 is an important mediator of SPARC (show SPARC Proteins)-regulated cardiac aging.

  3. research emphasises the importance of ADAMTS5 (show ADAMTS5 Proteins) expression in the control of influenza virus infection and highlights the potential for development of ADAMTS5 (show ADAMTS5 Proteins)-based therapeutic strategies to reduce morbidity and mortality

  4. increased expression of ADAMTS1 protein in macrophages and neutrophils that infiltrated aortic tissues may promote the progression of acute aortic dissection

  5. TS5 protein functions to suppress glucose uptake in adipose-derived stromal cells and thereby inhibits the synthesis, and promotes the intracellular degradation of Acan (show ACAN Proteins) and Vcan (show Vcan Proteins) by an ADAMTS other than TS5.

  6. Data suggest that ADAMTS-5 (show ADAMTS5 Proteins) oligomerization is required for full aggrecanase (show ADAMTS4 Proteins) activity in vitro and in situ (as seen in knee joint of mouse model of inflammatory arthritis); thus, blocking oligomerization inhibits ADAMTS-5 (show ADAMTS5 Proteins) activity.

  7. The resilience of casp1 (show CASP1 Proteins)(-/-) mice to SIRS lethality is associated with a lower inflammatory response, loss of hippocampal gene coexpression patterns, and increased hippocampal Adamts1 gene expression.

  8. Adamts-1 upregulation by inducers of pathological vascular remodeling is mediated by specific signal transduction pathways involving NFAT (show NFATC1 Proteins) or C/EBPbeta (show CEBPB Proteins) transcription factors.

  9. aggrecan (show ACAN Proteins) and brevican (show BCAN Proteins) proteolysis is compensated in Adamts4 (show ADAMTS4 Proteins)-/- or Adamts5 (show ADAMTS5 Proteins)-/- mice by ADAMTS proteoglycanase (show MMP3 Proteins) family members but a threshold of versican (show Vcan Proteins) proteolysis is sensitive to the loss of a single ADAMTS proteoglycanase (show MMP3 Proteins) during spinal cord injury

  10. The present study reveals ADAMT-5 expression by mast cells(MCs (show SMCP Proteins)) and that MC activation regulates the expression of the protease, thus implicating the ADAMT-5 of protease in MC function.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. Patients with Marfan syndrome showed elevated NOS2 (show NANOS2 Proteins) and decreased ADAMTS1 protein levels in the aorta.

  2. Data indicate that serum versican (show Vcan Proteins) levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican (show Vcan Proteins) levels were significantly and positively correlated with each other.

  3. Findings indicate that ADAMTS-1 has proteolytic functions in the nucleus through its interaction with aggrecan (show ACAN Proteins) substrate in normal and tumoral breast cells.

  4. All ADAMTS (show ADAMTS13 Proteins) tested in our study were expressed in both stable and unstable carotid plaques, especially in smooth muscle cells and macrophages. Analysis of the expression pattern on mRNA level showed significant higher expression of ADAMTS1 in unstable plaques compared with stable plaques.

  5. ADAMTS1 protein levels in semen were significantly lower in males with infertility. Sperm count and motility showed a negative correlation with levels of ADAMTS1 protein expression.

  6. increased expression of ADAMTS1 protein in macrophages and neutrophils that infiltrated aortic tissues may promote the progression of acute aortic dissection

  7. High ADAMTS1 expression was significantly associated with tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.

  8. progesterone acts via the progesterone receptor (show PGR Proteins) to modulate ADAMTS 1 and 4 levels in ovarian cancer cell lines.

  9. Data suggest that the rs416905 and rs402007 single nucleotide polymorphisms of the a disintegrin and metallo-proteinase with thrombospondin type 1 motifs (ADAMTS-1) gene may be associated with ischemic stroke caused by large artery atherosclerosis (LAA).

  10. Results show that ADAMTS1 expression is negatively regulated in breast neoplasm cells due to mir-365 targeting its 3'UTR.

Pig (Porcine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. Expression and induction of ADAMTS-1 through receptor-mediated action of progesterone in cumulus cells is one of essential requirements for gonadotropin-regulated cumulus expansion of porcine cumulus-oocyte complexes.

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1) interaction partners

  1. study indicates that disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) participates in bovine endometrial remodeling

  2. Data indicate that ADAMTS1 promoter activity and mRNA expression were increased by forskolin and human chorionic gonadotropin.

ADAMTS1 Protein Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Gene names and symbols associated with ADAMTS1

  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (adamts1)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 1 (Adamts1)
  • 9530092O11Rik protein
  • ADAM-TS1 protein
  • ADAM-TS5 protein
  • ADAMTS protein
  • ADAMTS-1 protein
  • ADAMTS1 protein
  • ADAMTS11 protein
  • AI481094 protein
  • ASMP-2 protein
  • C3-C5 protein
  • METH-1 protein
  • METH1 protein
  • xadamts1 protein

Protein level used designations for ADAMTS1

metalloproteinase with thrombospondin-like motifs-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 1 , A disintegrin and metalloproteinase with thrombospondin motifs 1 , ADAM-TS 1 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 , A disintegrin and metalloproteinase with thrombospondin motifs 5 , ADAM-TS 5 , ADAMTS-5 , ADMP-2 , aggrecanase-2 , implantin , ADAM-TS1 , ADAMTS-1 , METH-1 , human metalloproteinase with thrombospondin type 1 motifs , a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1) , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 , a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1

GENE ID SPECIES
791251 Equus caballus
565145 Danio rerio
100548786 Meleagris gallopavo
100151734 Xenopus (Silurana) tropicalis
11504 Mus musculus
23794 Mus musculus
9510 Homo sapiens
418479 Gallus gallus
497061 Sus scrofa
512171 Bos taurus
79252 Rattus norvegicus
100415773 Ovis aries
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