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ALX Homeobox 3 Proteins (ALX3)

ALX3 encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Additionally we are shipping ALX3 Antibodies (26) and ALX3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALX3 257 O95076
Rat ALX3 ALX3 365900  
ALX3 11694 O70137
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Top ALX3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ALX3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for ALX Homeobox 3 (ALX3) Interaction Partners

Human ALX Homeobox 3 (ALX3) interaction partners

  1. Exclusion of mutations in ALX3 gene in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies

  2. We report a novel Y214X mutation in ALX3 in frontorhiny.

  3. The lack of a chromosome 1-derived fragment of ALX3 in restriction landmark genomic scanning and virtual genome scans of neuroblastomas is attributable to hypermethylation.

  4. Chromatin immunoprecipitation assays indicated that Alx3 in mouse pancreatic islets occupies the promoter of the mouse insulin (show INS Proteins) genes.

  5. ALX3 is essential for normal facial development in humans and that deficiency causes a clinically recognizable phenotype, which we term frontorhiny.

  6. Rat Alx3 undergoes restrictive or permissive interactions with nuclear proteins that determine its binding to and transactivation from TAAT target sites selected in a cell-specific manner.

Mouse (Murine) ALX Homeobox 3 (ALX3) interaction partners

  1. Pdx1 (show PDX1 Proteins), USF1 (show USF1 Proteins) and USF2 (show USF2 Proteins) co-ordinately regulate Alx3 gene expression in pancreatic beta-cells.

  2. Alx3 promoter activity in mesenchymal and pancreatic cells is regulatd by USF transcription factors and Twist1 (show TWIST1 Proteins)

  3. ALX3 could be considered as a candidate gene for the etiopathogenesis of diabetes or its complications during embryonic or fetal development is discussed

  4. ALX3 participates in the regulation of the expression of essential genes for the function of pancreatic islets, and its deficiency alters the regulation of glucose homeostasis in vivo.

  5. Alx3-deficient mice exhibit folic acid-resistant craniofacial midline and neural tube closure defects.

ALX3 Protein Profile

Protein Summary

This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors.

Gene names and symbols associated with ALX Homeobox 3 Proteins (ALX3)

  • ALX homeobox 3 (ALX3)
  • ALX homeobox 3 (Alx3)
  • aristaless-like homeobox 3 (Alx3)
  • ALX3 protein
  • FND1 protein

Protein level used designations for ALX Homeobox 3 Proteins (ALX3)

ALX homeobox 3 , aristaless-like homeobox 3 , homeobox protein aristaless-like 3 , proline-rich transcription factor ALX3 , aristaless 3 , proline-rich transcription factor Alx3

GENE ID SPECIES
469416 Pan troglodytes
522085 Bos taurus
700927 Macaca mulatta
257 Homo sapiens
365900 Rattus norvegicus
11694 Mus musculus
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