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Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Additionally we are shipping AMER2 Antibodies (5) and AMER2 Kits (3) and many more products for this protein.
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the Amer2-EB1 (show MAPRE1 Proteins)-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.
FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor (show RASGRF1 Proteins) ARHGEF2 (show ARHGEF2 Proteins) to decrease actomyosin contractility.
the Amer2-EB1 (show MAPRE2 Proteins)-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.
data characterize Amer2 for the first time as a negative regulator of Wnt (show WNT2 Proteins) signaling both in cell lines and in vivo and define Amer proteins as a novel family of Wnt (show WNT2 Proteins) pathway regulators.
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity).
APC membrane recruitment protein 2
, family with sequence similarity 123, member A
, protein FAM123A
, family with sequence similarity 123A