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AT Rich Interactive Domain 5B (MRF1-Like) Proteins (ARID5B)

ARID5B encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. Additionally we are shipping ARID5B Antibodies (33) and ARID5B Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARID5B 84159 Q14865
ARID5B 71371 Q8BM75
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Top ARID5B Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ARID5B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B) Interaction Partners

Xenopus laevis AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B) interaction partners

  1. arid5b isoform1 and isoform2 are differentially expressed during development. Isoform1 is strongly expressed maternally, while isoform2 expression is essentially restricted to tailbud stages. arid5b is predominantly expressed in the developing pronephros.

Human AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B) interaction partners

  1. Non-coding variant rs10821936 in ARID5B was strongly associated with childhood B-cell acute lymphoblastic leukemia. No coding variants were associated with B-ALL susceptibility.

  2. variants within IKZF1 (show IKZF1 Proteins), ARID5B, and CEBPE (show CEBPE Proteins) were associated with increased acute lymphoblastic leukemia (ALL) risk, and the effects for ARID5B and CEBPE (show CEBPE Proteins) were most prominent in high-hyperdiploid ALL subtype in the California Hispanic population

  3. Data indicate no significant associations of transcription factors rs4132601 (IKZF1), rs7089424 (ARID5B) and rs2239633 (CEBPE) with risk of pediatric non-Hodgkin lymphoma (NHL).

  4. Interactions between rs10740055 in ARID5B or rs4132601 in IKZF1 and each of the suspected non-genetic factors were tested.

  5. These results evidence that interaction of genetic variants in ARID5B and IKZF1 and environmental exposures may further alter risk of childhood acute lymphoblastic leukemia.

  6. ARID5B polymorphism confers an increased risk to acquire specific MLL (show MLL Proteins) rearrangements in early childhood leukemia.

  7. Our findings confirm the association of novel genetic variations in folate-related and ARID5B genes with the serum MTX (show MTX1 Proteins) levels and acute toxicity.

  8. We found that rs7073837 in ARID5B correlated with a risk for childhood B lineage ALL.

  9. study found that previously identified childhood acute lymphoblastic leukemia susceptibility loci in ARID5B and CEBPE (show CEBPE Proteins) show consistent risk effects across both Hispanic and non-Hispanic White populations, providing compelling supportive evidence for susceptibility at these loci

  10. Germline variants in IKZF1 (show IKZF1 Proteins), ARID5B, and CEBPE (show CEBPE Proteins) as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group.

Mouse (Murine) AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B) interaction partners

  1. These results strongly suggest that p62 plays a crucial role in preventing fenofibrate-induced cell death.

  2. Arid5b recruits Phf2 (show PHF2 Proteins) to the promoter region of Sox9 (show SOX9 Proteins) target genes and stimulates H3K9me2 demethylation of these genes.

  3. knockdown of Mrf-2 increases the rate of fatty acid recycling in 3T3-L1-derived adipocytes.

  4. phenotypes suggest that Mrf-2 is essential for accumulation of lipid stores in postnatal life

  5. Data suggest that Mrf-2 facilitates the induction of key adipogenic transcription factors C/EBPalpha (show CEBPA Proteins) and peroxisome proliferator-activated receptor-gamma (show PPARG Proteins).

  6. These results indicate that Mrf2 can be a potential regulator of adipocyte differentiation and a potential repressor of leptin (show LEP Proteins).

ARID5B Protein Profile

Protein Summary

This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ARID5B

  • AT rich interactive domain 5B (MRF1-like) (ARID5B)
  • AT rich interactive domain 5B (MRF1-like) (LOC100352095)
  • AT rich interactive domain 5B (MRF1-like) (arid5b)
  • AT rich interactive domain 5B (MRF1-like) (Arid5b)
  • 4930580B11 protein
  • 5430435G07Rik protein
  • AI467247 protein
  • ARID5B protein
  • Desrt protein
  • DKFZp469H121 protein
  • DKFZP469L1210 protein
  • MRF-2 protein
  • Mrf2 protein
  • Mrf2alpha protein
  • Mrf2beta protein

Protein level used designations for ARID5B

AT rich interactive domain 5B (MRF1-like) , AT-rich interactive domain-containing protein 5B , AT-rich interactive domain-containing protein 5B-like , ARID domain-containing protein 5B , MRF1-like protein , modulator recognition factor 2 (MRF2) , ARID class DNA binding protein , AT rich interactive domain 5B (Mrf1 like) , MRF-2 , developmentally and sexually retarded with transient immune abnormalities protein , modulator recognition factor 2 , modulator recognition factor protein 2

GENE ID SPECIES
698639 Macaca mulatta
745725 Pan troglodytes
100017985 Monodelphis domestica
100072374 Equus caballus
100079189 Ornithorhynchus anatinus
100172166 Pongo abelii
100352095 Oryctolagus cuniculus
100381123 Xenopus laevis
100401292 Callithrix jacchus
100478552 Ailuropoda melanoleuca
100583448 Nomascus leucogenys
84159 Homo sapiens
71371 Mus musculus
783538 Bos taurus
423661 Gallus gallus
479217 Canis lupus familiaris
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