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ATM Interactor Proteins (ATMIN)

Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Additionally we are shipping ATM Interactor Antibodies (35) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATMIN 23300 O43313
ATMIN 234776 Q6P9S1
Rat ATMIN ATMIN 315037  
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Top ATM Interactor Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ATMIN Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for ATM Interactor (ATMIN) Interaction Partners

Human ATM Interactor (ATMIN) interaction partners

  1. ATMIN is required for cell cycle progression and chromosome segregation following replication stress.ATMIN is required for the ATM (show ATM Proteins)-mediated signaling and recruitment of 53BP1 (show TP53BP1 Proteins) to DNA damage sites upon replication stress.

  2. The ASCIZ-DYNLL1 (show DYNLL1 Proteins) feedback loop represents a novel mechanism for auto-regulation of gene expression, where the gene product directly inhibits the transcriptional activator while bound at its own promoter.

  3. these results imply a potential cellular interference between DYNLL1 (show DYNLL1 Proteins) and ATMIN functions.

  4. Asciz (Atmin) deletion or knock-down does not affect ATM levels and activation in mouse, chicken, or human cells

  5. ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein (ASCIZ) required for repair of abasic sites after methylating and oxidative DNA damage but not double-strand breaks. Forms DNA damage-induced foci with RAD51 (show RAD51 Proteins) and ssDNA. ASCIZ foci depend on MLH1 (show MLH1 Proteins).

  6. ATMIN defines a novel NBS1 (show NBN Proteins)-independent pathway of ATM (show ATM Proteins) signalling.

  7. These data suggest that ASCIZ may affect the choice between competing base repair pathways in a manner that reduces the amount of substrates available for Ig gene conversion.

  8. ASCIZ (ATMIN) is structurally related to the yeast ATM (show ATM Proteins)/ATR (show ANTXR1 Proteins) substrate Mdt1 (show RDH11 Proteins) (Pin4 (show PIN4 Proteins)/Ybl051c); both proteins contain SQ/TQ cluster domains and interact with N-terminal FHA (show CRY2 Proteins) domains of CHK2/Rad53 (show CHEK2 Proteins) kinases.

Mouse (Murine) ATM Interactor (ATMIN) interaction partners

  1. findings reveal a novel model for an intestinal bowel disease phenotype that occurs upon combined loss of the DNA repair cofactors ATMIN and NBS1 (show NBN Proteins)

  2. Results show that Atmin is critical for normal kidney development through Wnt (show WNT2 Proteins) signaling pathway modifications.

  3. ATMIN has a role in lung morphogenesis and ciliogenesis through transcriptional regulation

  4. UBR5-mediated ATMIN ubiquitination is a vital event for ATM (show ATM Proteins) pathway selection and activation in response to DNA damage

  5. the antagonism and redundancy of ATMIN and NBS1 (show NBN Proteins) constitute a crucial regulatory mechanism for ATM (show ATM Proteins) signaling and function.

  6. ASCIZ (ATMIN) regulates B cell development by inducing DYNLL1 (LC8 (show DYNLL1 Proteins)) expression which in turn prevents Bim (show BCL2L11 Proteins)-dependent apoptosis in immature B cells in the bone marrow

  7. The ASCIZ-DYNLL1 (show DYNLL1 Proteins) feedback loop represents a novel mechanism for auto-regulation of gene expression, where the gene product directly inhibits the transcriptional activator while bound at its own promoter.

  8. ATMIN has dual functions as an efficiency factor for DNA base damage repair as well as a key transcriptional regulator of early lung development.

  9. Identify a role for ATMIN in regulating the maintenance of genomic stability and tumor suppression in B cells.

  10. Asciz is essential for mouse embryonic development and lung organogenesis likely as a transcription factor

ATM Interactor (ATMIN) Protein Profile

Protein Summary

Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.

Gene names and symbols associated with ATM Interactor Proteins (ATMIN)

  • ATM interactor (ATMIN)
  • ATM interactor (atmin)
  • centromere protein N (CENPN)
  • similar to ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein (LOC571606)
  • ATM interactor (Atmin)
  • Asciz protein
  • ATMIN protein
  • mKIAA0431 protein
  • RGD1305781 protein
  • ZNF822 protein

Protein level used designations for ATM Interactor Proteins (ATMIN)

ATM interactor , ATM INteracting protein , ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein , ATM/ATR-substrate CHEK2-interacting zinc finger protein , ATM/ATR-substrate CHK2-interacting zinc finger protein , zinc finger protein 822 , ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein

GENE ID SPECIES
426138 Gallus gallus
443691 Xenopus laevis
479635 Canis lupus familiaris
571606 Danio rerio
717395 Macaca mulatta
738730 Pan troglodytes
100031731 Monodelphis domestica
100069801 Equus caballus
100356797 Oryctolagus cuniculus
100449573 Pongo abelii
100483255 Ailuropoda melanoleuca
100487308 Xenopus (Silurana) tropicalis
100548302 Meleagris gallopavo
100565641 Anolis carolinensis
100585291 Nomascus leucogenys
23300 Homo sapiens
781217 Bos taurus
234776 Mus musculus
315037 Rattus norvegicus
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