You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 Proteins (ABCA7)

The protein encoded by ABCA7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA7 Antibodies (54) and ABCA7 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABCA7 27403 Q91V24
ABCA7 10347 Q8IZY2
Rat ABCA7 ABCA7 299609 Q7TNJ2
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ABCA7 Proteins at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

ABCA7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

More Proteins for ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) Interaction Partners

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. This study demonstrated that novel mechanism underlying how dysfunctions of ABCA7 contribute to the risk for alzheimer disease.

  2. ABCA7 has a role in Alzheimer amyloid processing

  3. Theresults of this study suggested that ABCA7 plays a role in the regulation of Abeta (show APP Proteins) homeostasis in the brain and that this may be related to altered phagocyte function.

  4. ABCA7 may play a role in T cell proliferation and erythropoeisis in spleen

  5. concluded that statins enhance macrophage phagocytosis through the SREBP-ABCA7 pathway.

  6. Data suggest that extracellular helical apolipoproteins augment ABCA7-associated phagocytosis by stabilizing ABCA7, and show direct enhancement of the host defense system by HDL (show HSD11B1 Proteins) components.

  7. ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and has a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues

  8. genetic knockdown of ABCA7 in mouse peritoneal macrophages did not affect phospholipid or cholesterol efflux to apoA-I (show APOA1 Proteins)

  9. ABCA7 plays a novel role in lipid and fat metabolism

  10. Mouse spermatozoa in the seminiferous tubules and epididymis express ABCA1 (show ABCA1 Proteins), ABCA7 and ABCG1 (show ABCG1 Proteins).

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. Studies indicate that ATP-binding cassette transporter (show ABCA4 Proteins) A7 (ABCA7) single nucleotide polymorphisms (SNPs) that increase Alzheimer's disease (AD) risk.

  2. Study replicates the association of ABCA7 loss-of-function variants with Alzheimer's disease risk, and highlights the necessity of performing gene-based, rather than single-variant analyses to replicate the association in this type of studies

  3. ABCA7 has a role in Alzheimer amyloid processing

  4. The results are consistent with the view that assembly of HDL particles with extracellular apoA-I is primarily with the cellular phospholipid molecules being regulated in part by their physicochemical nature.

  5. Loss-of-function of ABCA7 could be a potential mechanism of Alzheimer's disease as shown in a Belgian cohort.

  6. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease in Icelanders. [meta-analysis]

  7. Collectively, our analysis further supports previous findings that the ABCA7 rs3764650 polymorphism is associated with Alzheimer disease susceptibility.

  8. Brain DNA methylation (show HELLS Proteins) in ABCA7 was associated with pathological Alzheimer disease.

  9. It is a susceptibility gene of Alzheimer's disease in the Han-Chinese in Taiwan.

  10. ABCA7 (rs3,764,650) was associated with sporadic Alzheimer disease in the Chinese population, with both ApoEepsilon4-carrier and aging being factors enhancing its risk.

ABCA7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known\; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.

Gene names and symbols associated with ABCA7

  • ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7)
  • ATP-binding cassette, sub-family A (ABC1), member 7 (Abca7)
  • ATP-binding cassette, subfamily A (ABC1), member 7 (Abca7)
  • Abc51 protein
  • ABCA-SSN protein
  • ABCA7 protein
  • ABCX protein

Protein level used designations for ABCA7

ATP-binding cassette sub-family A member 7 , ATP-binding cassette, sub-family A, member 7 , ATP-binding cassette, sub-family A (ABC1), member 7 , autoantigen SS-N , macrophage ABC transporter

GENE ID SPECIES
511762 Bos taurus
455538 Pan troglodytes
468639 Pan troglodytes
485090 Canis lupus familiaris
704976 Macaca mulatta
100088822 Ornithorhynchus anatinus
100623892 Sus scrofa
27403 Mus musculus
10347 Homo sapiens
299609 Rattus norvegicus
Selected quality suppliers for ABCA7 Proteins (ABCA7)
Did you look for something else?