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Cleaves peptides in various proteins in a process that requires ATP hydrolysis.
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Comparison of the proteomics phenotype of clpp3-1 with the clpr2-1 and clpr4-1 phenotypes indicated very similar metabolic and protein homeostasis defects for these Clp core mutants.
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).