anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) Antibodies

The protein encoded by ABCG8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG8 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCG8 64241 Q9H221
ABCG8 67470 Q9DBM0
ABCG8 155192 P58428
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Top anti-ABCG8 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of ABCG8, using ABIN152887. Samples: mouse liver microsomes from G5/G8 knockout mice, wildtype human G5/G8, and transgenic human G5/G8. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: ABCG8 Antibody [ABIN438175] - Total protein from Mouse small intestine was separated on a 7.5% gel by SDS-PAGE and transferred to PVDF membrane. The membrane was then probed with anti-ABCG8 antibody at 2 ug/ml and detected with an anti-rabbit HRP conjugated secondary antibody using chemiluminescence. Immunocytochemistry/Immunofluorescence: ABCG8 Antibody [ABIN438175] - ABCG8 antibody was tested in HEK293 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.2 mL Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry: ABCG8 Antibody (1B10A5) [NBP1-71706] - Immunohistochemical analysis of ABCG8 in mouse intestine using NBP1-71706. Western Blot: ABCG8 Antibody (1B10A5) [NBP1-71706] - Analysis of ABCG8 expression in ABCG8 lysate using NBP1-71706. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ABCG8 Antibody [NBP1-83388] - Staining of human cell line U-251MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: ABCG8 Antibody [NBP1-83388] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver labeled with Anti-STSL/ABCG8 Polyclonal Antibody, Unconjugated (ABIN1387509) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$357.50
Details
Human Rabbit Biotin WB   0.1 mL Log in to see 7 to 9 Days
$500.06
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ELISA, WB The ABCG8 Antibody is used in Western blot to detect ABCG8 in human fetal liver lysates. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 7 to 9 Days
$793.83
Details

ABCG8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


Top referenced anti-ABCG8 Antibodies

  1. Human Polyclonal ABCG8 Primary Antibody for ICC, IF - ABIN152894 : Mathur, Watt, Field: Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid. in Journal of lipid research 2007 (PubMed)
    Show all 10 references for 152894

  2. Human Polyclonal ABCG8 Primary Antibody for WB - ABIN152887 : Garcia, Wilund, Arca, Zuliani, Fellin, Maioli, Calandra, Bertolini, Cossu, Grishin, Barnes, Cohen, Hobbs: Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. in Science (New York, N.Y.) 2001 (PubMed)
    Show all 8 references for 152887

  3. Human Monoclonal ABCG8 Primary Antibody for ICC, IF - ABIN4277252 : Graf, Yu, Li, Gerard, Tuma, Cohen, Hobbs: ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. in The Journal of biological chemistry 2003 (PubMed)
    Show all 7 references for 4277252

  4. Human Polyclonal ABCG8 Primary Antibody for WB - ABIN438154 : Maqdasy, El Hajjaji, Baptissart, Viennois, Oumeddour, Brugnon, Trousson, Tauveron, Volle, Lobaccaro, Baron: Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model. in Endocrinology 2015 (PubMed)

  5. Human Polyclonal ABCG8 Primary Antibody for ICC, IF - ABIN4277253 : Ahn, Jang, Jun, Lee, Shin: Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease. in Digestive diseases and sciences 2014 (PubMed)

More Antibodies against ABCG8 Interaction Partners

Human ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) interaction partners

  1. ABCG8 genetic variants may have role in the development of cholelithiasis in patients with Gaucher disease type 1.

  2. Genetic polymorphism within the ABCG8 gene is a risk factor for diabetes.

  3. crystallization in lipid bilayers to determine the X-ray structure of human G5G8 in a nucleotide-free state at 3.9 A resolution, generating the first atomic model of an ABC (show ABCB6 Antibodies) sterol transporter

  4. A polymorphism of the sterol transporter ABCG8 has been associated with the prevalence of end-stage renal disease

  5. Mutation in ABCG8 is associated with sitosterolaemia.

  6. ATP-binding cassette (ABC (show ABCB6 Antibodies)) transporters G5 (ABCG5 (show ABCG5 Antibodies)) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of cholesterol and phytosterols.

  7. ABCG5 (show ABCG5 Antibodies)/8 variants are associated with susceptibility to coronary heart disease.

  8. Sitosterolemia is caused by a genetic defect of sterolins (ABCG5 (show ABCG5 Antibodies)/ABCG8) mapped to the STSL (show ABCG5 Antibodies) locus. Polymorphic variations in STSL (show ABCG5 Antibodies) have been linked to lipid levels and gallstone disease

  9. HRD1 (show SYVN1 Antibodies) and RMA1 may therefore be negative regulators of disease-associated transporter ABCG5 (show ABCG5 Antibodies)/ABCG8.

  10. MI and gallstones, 2 seemingly unrelated diseases, are intrinsically linked via the function of the ABCG5 (show ABCG5 Antibodies)/8 cholesterol transporter.

Mouse (Murine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) interaction partners

  1. The ABCG5 (show ABCG5 Antibodies)/G8-independent pathway plays an important role in regulating biliary cholesterol secretion, and gallstone formation, which works independently of the ABCG5 (show ABCG5 Antibodies)/G8 pathway.

  2. ABCG5 (show ABCG5 Antibodies)/G8 mediate mass biliary cholesterol secretion but not from a reverse cholesterol transport-relevant pool.

  3. AdGRP78 reduced expression of lipogenic genes and plasma triglycerides in the db/db (show LEPR Antibodies) strain. Both G5 and G8 protein levels increased as did total biliary cholesterol

  4. The data demonstrate that Abcg5 (show ABCG5 Antibodies)/Abcg8 deficiency reduces the uptake and secretion of both dietary triacylglycerols and cholesterol by the intestine, suggesting a novel role for the sterol transporter in the formation and secretion of chylomicrons.

  5. Sitosterolemia is caused by a genetic defect of sterolins (ABCG5 (show ABCG5 Antibodies)/ABCG8) mapped to the STSL locus. Polymorphic variations in STSL have been linked to lipid levels and gallstone disease

  6. The absence of an ABCG5 (show ABCG5 Antibodies)/ABCG8 expression.

  7. biliary cholesterol mass secretion under maximal bile salt-stimulated conditions is fully dependent on ABCG5 (show ABCG5 Antibodies)/G8

  8. This study is the first to report such toxic effects of phytosterol accumulation in ABCG5 (show ABCG5 Antibodies)/G8 knockout mice.

  9. handling of sterols by the intestine involves both G5G8 and ACAT2 but that an additional factor (possibly Niemann-Pick C1-like 1) may be key in determining absorption efficiency

  10. The ABCG5 (show ABCG5 Antibodies) ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation

Cow (Bovine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) interaction partners

  1. high expression levels of both ATP-binding cassette sub-family G member 5 (show ABCG5 Antibodies) and 8 (ABCG5 (show ABCG5 Antibodies) and ABCG8) were present in bovine liver and digestive tract samples, and in the mammary gland

ABCG8 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

Gene names and symbols associated with ABCG8

  • ATP-binding cassette, sub-family G (WHITE), member 8 (ABCG8) antibody
  • ATP-binding cassette sub-family G member 8 (PTRG_02054) antibody
  • ABC transporter G family protein (abcG8) antibody
  • ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8) antibody
  • ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8) antibody
  • ATP-binding cassette, subfamily G (WHITE), member 8 (Abcg8) antibody
  • 1300003C16Rik antibody
  • AI114946 antibody
  • DDBDRAFT_0167690 antibody
  • DDBDRAFT_0191232 antibody
  • DDB_0167690 antibody
  • DDB_0191232 antibody
  • GBD4 antibody
  • sterolin-2 antibody
  • STSL antibody
  • zgc:172358 antibody

Protein level used designations for ABCG8

ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) , sterolin 2 , ATP-binding cassette sub-family G member 8 , sterolin-2 , ATP-binding cassette, sub-family G (WHITE), member 8 , ATP-binding cassette sub-family G member 8-like , ATP-binding cassette, subfamily G, member 8

GENE ID SPECIES
100069071 Equus caballus
421402 Gallus gallus
470363 Pan troglodytes
6338845 Pyrenophora tritici-repentis Pt-1C-BFP
8619568 Dictyostelium discoideum AX4
100033372 Monodelphis domestica
100136850 Danio rerio
100350554 Oryctolagus cuniculus
100402530 Callithrix jacchus
100445033 Pongo abelii
100466630 Ailuropoda melanoleuca
100601594 Nomascus leucogenys
64241 Homo sapiens
67470 Mus musculus
474571 Canis lupus familiaris
100048963 Sus scrofa
508829 Bos taurus
155192 Rattus norvegicus
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