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ATPase, Ca++ Transporting, Ubiquitous Proteins (ATP2A3)

ATP2A3 encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. Additionally we are shipping ATP2A3 Antibodies (31) and ATP2A3 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATP2A3 53313 Q64518
Rat ATP2A3 ATP2A3 25391 P18596
ATP2A3 489 Q93084
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Top ATP2A3 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ATP2A3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) Interaction Partners

Xenopus laevis ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) interaction partners

  1. atp2a3/serca3 expression is restricted to the ectoderm throughout development

Mouse (Murine) ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) interaction partners

  1. ANP (show NPPA Proteins) counter-regulates cardiac MR activation in hypertensive heart disease. An imbalance in cardiac ANP (show NPPA Proteins)/GC-A (show GUCA1A Proteins) (inhibition) and aldosterone/MR signaling (augmentation) favors adverse cardiac remodeling in chronic pressure overload.

  2. This study evaluated the role of SERCA2b (show ATP2A2 Proteins) and SERCA3 in the control of the free calcium concentration in the endoplasmic reticulum and the role of SERCA3 in the control of insulin (show INS Proteins) secretion.

  3. identification of promoter region and binding site for Ets-1 (show ETS1 Proteins) in mouse SERCA3

  4. Ablation does not impair insulin (show INS Proteins) secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2 (show CA2 Proteins)+) pumps for Ca(2 (show CA2 Proteins)+) homeostasis in pancreatic beta-cells

  5. regulation in insulin (show INS Proteins)-secreting beta-cells by insulin receptor substrate 1 (show IRS1 Proteins)

  6. IRS-1 (show IRS1 Proteins) modulation of insulin (show INS Proteins) secretion is associated with Ca(2 (show CA2 Proteins)+) signaling and expression of SERCA-2b and -3 genes in pancreatic islets. Direct link between insulin (show INS Proteins) resistance and defective insulin (show INS Proteins) secretion.

Human ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) interaction partners

  1. we make a comprehensive analysis of the current knowledge of the role of the SERCA pumps in the pathophysiology of insulin (show INS Proteins)-dependent diabetes mellitus type 1 (TIDM) and type 2 (T2DM) in the heart and beta-cells in the pancreas

  2. Normal choroid plexus epithelial cells express SERCA3 abundantly, SERCA3 expression is strongly decreased in papillomas, and is absent in choroid plexus carcinoma, while expression in hyperplastic epithelium is high, similarly to normal epithelium.

  3. aberrant SERCA3 expression is closely linked to the adenoma-adenocarcinoma sequence and progression of colorectal carcinomas.

  4. Loss of SERCA3 expression is associated with lung cancer.

  5. High SERCA3 expression is associated with pathogenesis, invasion, metastasis of gastric carcinomas.

  6. SERCA2 (show ATP2A2 Proteins) and SERCA3 isoforms have roles in the failing and failing human heart

  7. Data show that low Ca2 (show CA2 Proteins)+-affinity SERCA3, and the high Ca2 (show CA2 Proteins)+-affinity SERCA2 (show ATP2A2 Proteins) enzymes are simultaneously expressed in B cells, and decreased SERCA3 expression during EBV-infection.

  8. novel sarco/endoplasmic isoforms; data suggest that the SERCA3 gene products have a more widespread role in cellular Ca2 (show CA2 Proteins)+ signaling than previously appreciated

  9. SERCA3 constitutes an interesting new differentiation marker that may prove useful for the analysis of the phenotype of gastrointestinal adenocarcinomas.

  10. Results describe the catalytic cycle of three human SERCA3 isoenzymes: SERCA3a, b, and c.

ATP2A3 Protein Profile

Protein Summary

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with ATP2A3

  • ATPase, Ca++ transporting, ubiquitous (atp2a3)
  • ATPase, Ca++ transporting, ubiquitous (ATP2A3)
  • ATPase, Ca++ transporting, ubiquitous (Atp2a3)
  • Atp2a3 protein
  • SERCA protein
  • Serca3 protein
  • SERCA3b protein
  • si:dkey-205l20.1 protein

Protein level used designations for ATP2A3

ATPase, Ca++ transporting, ubiquitous , sarcoplasmic/endoplasmic reticulum calcium ATPase 3-like , SR Ca(2+)-ATPase 3 , calcium pump 3 , sarcoendoplasmic reticulum Ca2+ ATPase type 3 , sarcoplasmic/endoplasmic reticulum calcium ATPase 3 , ATPase, Ca(2+)-transporting, ubiquitous , adenosine triphosphatase, calcium , calcium-translocating P-type ATPase , sarco/endoplasmic reticulum Ca2+ -ATPase , SERCA3 , chkSERCA3 , sarcoendoplasmic reticulum calcium ATPase

GENE ID SPECIES
495440 Xenopus laevis
568671 Danio rerio
707768 Macaca mulatta
779786 Xenopus (Silurana) tropicalis
100174979 Cavia porcellus
100414635 Callithrix jacchus
100446409 Pongo abelii
100465699 Ailuropoda melanoleuca
100354976 Oryctolagus cuniculus
100072684 Equus caballus
100586790 Nomascus leucogenys
53313 Mus musculus
25391 Rattus norvegicus
489 Homo sapiens
491437 Canis lupus familiaris
512313 Bos taurus
395707 Gallus gallus
396820 Sus scrofa
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