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anti-ATPase Family, AAA Domain Containing 5 (ATAD5) Antibodies

Involved in DNA damage response. Additionally we are shipping ATPase Family, AAA Domain Containing 5 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATAD5 79915 Q96QE3
ATAD5 237877 Q4QY64
ATAD5 303348  
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Top anti-ATPase Family, AAA Domain Containing 5 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Mouse Goat Un-conjugated ELISA   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-Elg1 antibody shows detection of a band ~120 kDa corresponding to human Elg1 (arrowhead) in various cell lysates. Lanes contain ~ 5 ?g of HeLa nuclear extract (1), HeLa (2), A431 (3), Jurkat (4) and HEK293 (5) whole cell lysates. After SDS-PAGE, transfer and blocking, the membrane was probed with the primary antibody diluted to 1:500. The membrane was then washed and reacted with a HRP conjugated Gt-a-Rabbit IgG [H&L] MX followed by ECL detection using a 2 m exposure time. The expected molecular weight of Elg1 is 120kDa according to Kanellis P et al. 2003, although the predicted molecular weight is 207 kDa. The 50kD bands in Jurkat and 293 cell lysates are probably cross-reaction with other proteins. Both the 120 kDa and 50 kDa bands are not observed when antibody is pre-incubated with peptide (data not shown). 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti ATAD5 Polyclonal Antibody,Unconjugated (ABIN872440) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Mouse Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Mouse Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Rat Goat Alkaline Phosphatase (AP) ELISA   100 μL Log in to see 16 Days
$620.71
Details
Rat Goat PE ELISA   100 μL Log in to see 16 Days
$620.71
Details

ATAD5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-ATPase Family, AAA Domain Containing 5 Antibodies

  1. Human Polyclonal ATAD5 Primary Antibody for EIA, WB - ABIN401276 : Kanellis, Agyei, Durocher: Elg1 forms an alternative PCNA-interacting RFC complex required to maintain genome stability. in Current biology : CB 2003 (PubMed)
    Show all 2 references for ABIN401276

  2. Mouse (Murine) Polyclonal ATAD5 Primary Antibody for ELISA - ABIN190859 : Ishii, Inageta, Mimori, Saito, Sasaki, Isobe, Mori, Croce, Huebner, Ozawa, Furukawa: Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

More Antibodies against ATPase Family, AAA Domain Containing 5 Interaction Partners

Human ATPase Family, AAA Domain Containing 5 (ATAD5) interaction partners

  1. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia (show PALB2 Antibodies) pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review]

  2. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA (show PCNA Antibodies) levels on chromatin, thereby acting as a PCNA (show PCNA Antibodies) unloading factor.

  3. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA (show PCNA Antibodies)-unloading activity.

  4. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis.

  5. Studies indicate that USP1 (show USP1 Antibodies) and ELG1 as regulators of PCNA (show PCNA Antibodies) ubiquitylation.

  6. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci.

  7. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis.

Mouse (Murine) ATPase Family, AAA Domain Containing 5 (ATAD5) interaction partners

  1. Atad5+/m cells accumulate in the S phase, have decreased proliferation, and have reduced double-strand breaks, class switch recombination, and translocations

  2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia (show PALB2 Antibodies) pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review]

  3. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis.

ATPase Family, AAA Domain Containing 5 (ATAD5) Antigen Profile

Protein Summary

Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis.

Gene names and symbols associated with ATAD5

  • ATPase family, AAA domain containing 5 (ATAD5) antibody
  • ATPase family, AAA domain containing 5a (atad5a) antibody
  • ATPase family, AAA domain containing 5 (LOC100219192) antibody
  • ATPase family, AAA domain containing 5 (Atad5) antibody
  • atad5 antibody
  • C17orf41 antibody
  • C130052G03Rik antibody
  • cb14 antibody
  • ELG1 antibody
  • FRAG1 antibody
  • Gm17 antibody
  • im:7138471 antibody
  • RGD1561464 antibody
  • sb:cb14 antibody
  • si:ch211-11k18.10 antibody
  • Si:ch211-11k18.10 protein-like antibody
  • wu:fi03a11 antibody

Protein level used designations for ATAD5

ATPase family, AAA domain containing 5 , chromosome fragility associated gene 1 , ATPase family AAA domain-containing protein 5-like , ATPase family AAA domain-containing protein 5 , chromosome fragility-associated gene 1 protein , enhanced level of genomic instability 1 homolog , enhanced level of genomic instability gene 1

GENE ID SPECIES
454559 Pan troglodytes
560591 Danio rerio
100018805 Monodelphis domestica
100058527 Equus caballus
100350844 Oryctolagus cuniculus
100391218 Callithrix jacchus
100471983 Ailuropoda melanoleuca
100219192 Taeniopygia guttata
79915 Homo sapiens
237877 Mus musculus
417408 Gallus gallus
491156 Canis lupus familiaris
100522895 Sus scrofa
513059 Bos taurus
303348 Rattus norvegicus
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