You are viewing an incomplete version of our website. Please click to reload the website as full version.

Actin Filament Associated Protein 1 Proteins (AFAP1)

The protein encoded by AFAP1 is a Src binding partner. Additionally we are shipping AFAP Antibodies (98) and AFAP Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AFAP1 60312 Q8N556
AFAP1 70292 Q80YS6
AFAP1 140935 Q8VH46
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top AFAP Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,136.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 to 11 Days
$229.85
Details

AFAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Actin Filament Associated Protein 1 (AFAP1) Interaction Partners

Human Actin Filament Associated Protein 1 (AFAP1) interaction partners

  1. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1 (show ABCA1 Proteins)), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS (show GMDS Proteins)).

  2. Methylation of the long noncoding RNA AFAP1-AS1 (show PTGDR Proteins) is reduced in BE and EAC (show CYLD Proteins), and its expression inhibits cancer-related biologic functions of EAC (show CYLD Proteins) cells.

  3. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB 231 breast cancer cells.

Mouse (Murine) Actin Filament Associated Protein 1 (AFAP1) interaction partners

  1. These data define, for the first time, the requirement of AFAP1 for the spatial and temporal regulation of cSrc activity in the normal breast, specifically for milk production.

  2. In E16 mouse embryos, AFAP expression levels concentrated in the olfactory bulb, cortex, forebrain, cerebellum, and various peripheral sensory structures.In P3 mouse pups, overall expression was reduced. (AFAP-110)

  3. Data suggest that one major function of AFAP-110 is to relay signals from protein kinase C alpha that direct the activation of c-Src and the formation of podosomes.

  4. Actin filament associated protein-110 (AFAP) colocalizes with cSrc to promote cSrc activation and cell migration.

  5. AFAP120 may coordinate Src signaling with the dynamic changes in the actin cytoskeleton that drive growth cone motility and axon elongation.

  6. These results indicate that AFAP120 plays a role in organizing dynamic actin structures during neuronal differentiation and suggest that AFAP120 may help regulate the transition from motile precursor to morphologically differentiated neurons.

AFAP (AFAP1) Protein Profile

Protein Summary

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AFAP1

  • actin filament associated protein 1 (AFAP1)
  • actin filament associated protein 1 (afap1)
  • actin filament associated protein 1 (Afap1)
  • actin filament associated protein 1-like (LOC100339958)
  • 2600003E23Rik protein
  • 9630044L16Rik protein
  • Afap protein
  • AFAP-110 protein
  • AFAP110 protein
  • AI848729 protein
  • mKIAA3018 protein

Protein level used designations for AFAP1

actin filament associated protein 1 , actin filament-associated protein 1-like , 110 kDa actin filament-associated protein , actin filament-associated protein 1 , actin filament-associated protein, 110 kDa , AFAP-110 , neural actin filament protein , pp110

GENE ID SPECIES
461111 Pan troglodytes
779522 Xenopus (Silurana) tropicalis
100014539 Monodelphis domestica
100056653 Equus caballus
100454152 Pongo abelii
100466777 Ailuropoda melanoleuca
60312 Homo sapiens
70292 Mus musculus
140935 Rattus norvegicus
100735141 Cavia porcellus
100522448 Sus scrofa
374034 Gallus gallus
488786 Canis lupus familiaris
534032 Bos taurus
101109449 Ovis aries
100339958 Oryctolagus cuniculus
Selected quality suppliers for AFAP Proteins (AFAP1)
Did you look for something else?