Activin A Receptor Type II-Like 1 (ACVRL1) ELISA Kits

ACVRL1 encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. Additionally we are shipping ACVRL1 Antibodies (157) and ACVRL1 Proteins (21) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACVRL1 94 P37023
ACVRL1 25237 P80203
ACVRL1 11482 Q61288
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Top ACVRL1 ELISA Kits at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$870.62
Details
Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Mouse 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$707.14
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Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for ACVRL1 Interaction Partners

Cow (Bovine) Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. Results show that ALK5 (show TGFBR1 ELISA Kits) and ALK1 play antagonistic roles in TGF-beta (show TGFB1 ELISA Kits)-induced podosome formation in aortic endothelial cells.

  2. ALK1 and ALK5 are both essential for correct regulation of VEGF, and that disruption of either pathway leads to disease.

Zebrafish Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. alk1 loss has no effect on arterial endothelial cell proliferation but alters arterial endothelial cell migration within lumenized vessels.

  2. Control of Notch (show NOTCH1 ELISA Kits) targets in arterial endothelium is context-dependent, with gene-specific and region-specific requirements for Notch (show NOTCH1 ELISA Kits) and Alk1

  3. Blood flow is required not only for alk1 expression but also for Alk1 activity.

  4. Study demonstrate that alk1 expression requires blood flow, and despite normal levels of shear stress, some flow-responsive genes are dysregulated in alk1 mutant arterial endothelial cells.

  5. vbg encodes activin receptor-like kinase 1 (acvrl1), a TGFbeta (show TGFB1 ELISA Kits) type I receptor that is expressed predominantly in the endothelium of the vessels that become dilated in vbg mutants.

Human Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. c.1027C > T(p.Gln343) mutation within the ACVRL1 gene in family with hereditary hemorrhagic telangiectasia

  2. Bone morphogenetic protein (BMP)9 (show GDF2 ELISA Kits) and BMP10 (show BMP10 ELISA Kits) are high affinity ligands for activin receptor-like kinase 1 (ALK1).

  3. Activin receptor-like kinase (ALK)1 is a transforming growth factor beta (TGF-beta) type I receptor (show TGFBR1 ELISA Kits) predominantly expressed in actively proliferating endothelial cells (ECs).

  4. Two novel missense mutations and two recurrent mutations in the ACVRL1 gene are associated with pulmonary arterial hypertension in in Chinese families.

  5. ALK1 expression and microvessel density are increased in oral lichen planus , particularly in atrophic/erosive OLP type.

  6. The genetic-interactions among BMPR-2 (show BMPR2 ELISA Kits), ALK-1, and 5-HTT (show SLC6A4 ELISA Kits) polymorphisms, elevated BMP-2 (show BMP2 ELISA Kits) and 5-HT (show DDC ELISA Kits) levels and differential gene expression substantiated the strong genetic contribution in high altitude pulmonary edema pathophysiology.

  7. Study of four patients with pulmonary arterial hypertension associated with human immunodeficiency virus infection found predisposing mutations in the BMPR2 (show BMPR2 ELISA Kits), ACVRL1 and ENG (show ENG ELISA Kits) genes.

  8. The preponderance of ACVRL1 mutations was due to founder mutations, specifically, c.830C>A (p.Thr277Lys), which was found in 24 families from the same geographical area of Norway.

  9. Report interaction between ALK1 signaling and connexin40 in the development of arteriovenous malformations.

  10. Data suggest ALK1 and ACVR2A (show ACVR2A ELISA Kits)/ACVR2B (show ACVR2B ELISA Kits), acting as BMP9 (show GDF2 ELISA Kits) co-receptors, rearrange pro-domains of BMP9 (show GDF2 ELISA Kits)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

Mouse (Murine) Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. this study demonstrates that ACVRL1 signaling plays a pivotal role whereby it suppresses plasmacytoid dendritic cell development while enhancing that of CD8alpha(+) dendritic cells, thus contributing to DC diversity development.

  2. CD109 (show CD109 ELISA Kits) differentially regulates TGF-beta (show TGFB1 ELISA Kits)-induced ALK1-Smad1 (show SMAD1 ELISA Kits)/5 versus ALK5 (show TGFBR1 ELISA Kits)-Smad2 (show SMAD2 ELISA Kits)/3 pathways, leading to decreased extracellular matrix production in the skin; epidermal CD109 (show CD109 ELISA Kits) expression regulates dermal function through a paracrine mechanism

  3. he results of the present study demonstrated that BMP9 (show GDF2 ELISA Kits) promoted the osteoclast differentiation of osteoclast precursors via binding to the ALK1 receptor on the cell surface, and inhibiting the ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathways in the cell

  4. Conclude that the ALK-1 receptor is involved in the control of arterial pressure. High AP of Alk1(+/-) mice is explained mainly by the sympathetic overactivation, which is probably related to the decreased number of cholinergic neurons.

  5. Report interaction between ALK1 signaling and connexin40 in the development of arteriovenous malformations.

  6. In vascular sprouting, neuropilin-1 (show NRP1 ELISA Kits) suppresses the stalk-cell phenotype by limiting Smad2 (show SMAD2 ELISA Kits)/3 activation through Alk1 and Alk5 (show TGFBR1 ELISA Kits). Notch (show NOTCH1 ELISA Kits) downregulates Nrp1 (show NRP1 ELISA Kits), thus relieving the inhibition of Alk1 and Alk5 (show TGFBR1 ELISA Kits), thereby driving stalk-cell behaviour.

  7. BMP9 (show GDF2 ELISA Kits)/ALK1 augmented vasculogenesis and angiogenesis, and thereby enhanced neovascularization. Thus, we suggest that BMP9 (show GDF2 ELISA Kits)/ALK1 may improve the efficacy of EPC (show TCF21 ELISA Kits)-based therapies for treating ischemic diseases.

  8. BMP-9 (show GDF2 ELISA Kits) induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1, Smad (show SMAD1 ELISA Kits) and ALP dependent mechanisms.

  9. during development, endothelial Acvrl1 plays an essential role to regulate endothelial cell proliferation and arterial identity during angiogenesis, whilst in adult life endothelial Acvrl1 is required to maintain vascular integrity.

  10. Results show that ALK5 (show TGFBR1 ELISA Kits) and ALK1 play antagonistic roles in TGF-beta (show TGFB1 ELISA Kits)-induced podosome formation in aortic endothelial cells.

ACVRL1 Antigen Profile

Antigen Summary

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Gene names and symbols associated with ACVRL1

  • activin A receptor type II-like 1 (ACVRL1) antibody
  • activin A receptor type II-like 1 (acvrl1) antibody
  • activin A receptor type II-like 1 (Acvrl1) antibody
  • activin A receptor, type II-like 1 (Acvrl1) antibody
  • ACVRL1 antibody
  • Acvrlk1 antibody
  • AI115505 antibody
  • AI427544 antibody
  • ALK-1 antibody
  • Alk1 antibody
  • HHT antibody
  • HHT2 antibody
  • hm:zehn1109 antibody
  • ORW2 antibody
  • R-3 antibody
  • R3 antibody
  • SETHKIR antibody
  • SKR3 antibody
  • TSR-I antibody
  • vgb antibody
  • zehn1109 antibody

Protein level used designations for ACVRL1

activin A receptor type II-like 1 , serine/threonine-protein kinase receptor R3 , serine/threonine-protein kinase receptor R3-like , activin receptor-like kinase 1 , vbg , violet beauregarde , TGF-B superfamily receptor type I , activin A receptor, type II-like kinase 1 , Activin receptor like kinase 1 , SKR3 , TSR-I , ALK-1 , activin receptor-like kinase-1

GENE ID SPECIES
451910 Pan troglodytes
534536 Bos taurus
696471 Macaca mulatta
100061313 Equus caballus
100135773 Felis catus
100482358 Ailuropoda melanoleuca
266753 Danio rerio
94 Homo sapiens
25237 Rattus norvegicus
477603 Canis lupus familiaris
100153279 Sus scrofa
100172614 Pongo abelii
11482 Mus musculus
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