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ACSS1 encodes a mitochondrial acetyl-CoA synthetase enzyme. Additionally we are shipping ACSS1 Antibodies (27) and many more products for this protein.
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ACSS1 is essential for glucose-independent acetate-mediated cell survival and tumor growth.
acetylation of AceCS1 (show ACSS2 Proteins) is cyclic and that its rhythmicity requires a functional circadian clock and the NAD(+)-dependent deacetylase SIRT1 (show SIRT1 Proteins).
together with the trans-activation of the AceCS2 promoter, it is suggested that fasting-induced AceCS2 expression is largely contributed by KLF15
Findings demonstrate that activation of acetate by AceCS2 plays a pivotal role in thermogenesis, especially under low-glucose or ketogenic conditions, and is crucially required for survival.
This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
acetyl-coenzyme A synthetase 2-like, mitochondrial
, acyl-CoA synthetase short-chain family member 1
, acetyl-coenzyme A synthetase 2-like, mitochondrial-like
, acetate--CoA ligase 2
, acetyl-CoA synthetase 2