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Alcohol Dehydrogenase 4 (Class II), pi Polypeptide Proteins (ADH4)

ADH4 encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Additionally we are shipping ADH4 Antibodies (61) and ADH4 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADH4 127 P08319
ADH4 29646  
ADH4 26876 Q9QYY9
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Top ADH4 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Struthio camelus His tag   1 mg Log in to see 56 to 66 Days
$3,041.50
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$3,050.67
Details

ADH4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced ADH4 Proteins

  1. Human ADH4 Protein expressed in Wheat germ - ABIN1305983 : Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015 (PubMed)

More Proteins for Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4) Interaction Partners

Human Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4) interaction partners

  1. this current study provides substantial evidence that genetic polymorphisms of rs3805322 in the ADH4 gene may be associated with an increased risk of developing ESCC in two Chinese Han populations.

  2. This study confirmed the genetic heterogeneity of cluster headache, suggesting that mutations in the ADH4 gene might be related to cluster headache in a subset of cases.

  3. The serum expression of ADH4 protein correlates with the progression of esophageal cancer.

  4. common ADH (show AVP Proteins) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  5. expression levels of ADH4 mRNA and protein have found to be markedly reduced in hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues and significantly associated with survival.

  6. data suggest that ADH4 intronic variants play a role in alcohol dependence susceptibility in Italian populations

  7. Variants in the ADH1B and ADH4 genes may be protective against the development of some symptoms associated with alcohol dependence.

  8. Our results suggest that the analysed polymorphisms ofANKK1 and ADH4 can play an important part in the pathogenesis of alcohol abuse

  9. the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver ADH1E

  10. This study confirms the significant relationship of ADH4 variants with AD and related phenotypes.

Mouse (Murine) Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4) interaction partners

  1. This study demonistrated that adh1/adh4 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

  2. The results suggested that lack of Adh4 gene activity induces changes in the function of the dopamine system, findings which are compatible with a role of loss-of-function mutations in ADH4 as possible risk factors for parkinson disease.

  3. Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

  4. Studies of kinetic properties of mouse ADH2 in new variants with substitutions at position 47 find that the pK values are not lowered by Pro47 to His substitution, suggesting that His47 does not act as a catalytic base in deprotonation of the zinc ligand.

  5. Adh4 metabolizes the omega-oxidation of 20-HETE in cerebral microvascular smooth muscle and endothelium.

  6. Cellular expression of Adh4 in the GI tract was studied.

  7. The metabolism of all-trans- and 9-cis (show RDH11 Proteins)-retinol/ retinaldehyde has been investigated with focus on the activities of human, mouse and rat alcohol dehydrogenase 2 (ADH2 (show ADH1B Proteins)), an intriguing enzyme with apparently different functions in human and rodents.

ADH4 Protein Profile

Protein Summary

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Gene names and symbols associated with ADH4

  • alcohol dehydrogenase Adh4 (adh4)
  • alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4)
  • alcohol dehydrogenase 4 (class II), pi polypeptide (Adh4)
  • Ac1002 protein
  • ADH-1 protein
  • ADH-2 protein
  • Adh2 protein

Protein level used designations for ADH4

alcohol dehydrogenase Adh4 , alcohol dehydrogenase 4 , alcohol dehydrogenase class II pi chain , aldehyde reductase , ADH2 , alcohol dehydrogenase II , alcohol dehydrogenase class II , class II alcohol dehydrogenase, pi subunit , class II type ADH

GENE ID SPECIES
2542714 Schizosaccharomyces pombe 972h-
127 Homo sapiens
520508 Bos taurus
29646 Rattus norvegicus
26876 Mus musculus
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