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anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Antibodies

AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Additionally we are shipping AKR1C2 Kits (14) and AKR1C2 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AKR1C2 1646 P52895
Anti-Rat AKR1C2 AKR1C2 291283 Q6AYQ2
AKR1C2    
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Top anti-AKR1C2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB AKR1C2 Antibody (C-term) (ABIN656180) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO cells, using AKR1C2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB AKR1C2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. AKR1C2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 µg/lane).This demonstrates the AKR1C2 antibody detected the AKR1C2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-AKR1C2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate WB Suggested Anti-AKR1C2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AKR1C2 is approximately 0.3ng/ml as a capture antibody. Western Blot analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 monoclonal antibody (M03), clone 3C11.Lane 1: AKR1C2 transfected lysate(36.7 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB AKR1C2 polyclonal antibody (A01), Lot # CIL0060112QCS1 Western Blot analysis of AKR1C2 expression in HeLa . Western Blot analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 polyclonal antibody (A01).Lane1:AKR1C2 transfected lysate(37 KDa).Lane2:Non-transfected lysate. 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated WB AKR1C2 MaxPab polyclonal antibody. Western Blot analysis of AKR1C2 expression in human liver. Western Blot analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 MaxPab polyclonal antibody.Lane 1: AKR1C2 transfected lysate(35.53 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AKR1C2 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

AKR1C2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mammalian


Top referenced anti-AKR1C2 Antibodies

  1. Human Polyclonal AKR1C2 Primary Antibody for EIA, WB - ABIN950320 : Setlur, Chen, Hossain, Ha, Van Doren, Stenzel, Steiner, Oldridge, Kitabayashi, Banerjee, Chen, Schäfer, Horninger, Lee, Rubin, Klocker, Demichelis: Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)
    Show all 3 references for ABIN950320

  2. Human Monoclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN514927 : Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. in Drug metabolism and disposition: the biological fate of chemicals 2008 (PubMed)
    Show all 2 references for ABIN514927

  3. Human Polyclonal AKR1C2 Primary Antibody for WB - ABIN514925 : Ebert, Kisiela, Wsól, Maser: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29. in Chemico-biological interactions 2011 (PubMed)

  4. Human Polyclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN1534616 : Qin, Khanna, Cheng: Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein. in Gene 1994 (PubMed)

  5. Human Polyclonal AKR1C2 Primary Antibody for ELISA, WB - ABIN560582 : Su, Liao, Huang, Chu, Lin, Chang: Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis. in Toxicology 2008 (PubMed)

  6. Human Polyclonal AKR1C2 Primary Antibody for IHC (p), WB - ABIN656180 : Wang, Chorley, Pittman, Kleeberger, Brothers, Liu, Spira, Bell: Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. in PLoS ONE 2010 (PubMed)

More Antibodies against AKR1C2 Interaction Partners

Human Aldo-keto Reductase Family 1, Member C2 (AKR1C2) interaction partners

  1. We identified two powerful genes in the liver cancer metastasis process, AEG-1 (show MTDH Antibodies) and AKR1C2.

  2. Identify two novel factors, AKR1C2 (positive factor) and NF1 (show NF1 Antibodies) (negative factor), as the AEG-1 (show MTDH Antibodies) downstream players in the process of metastasis in liver cancer.

  3. The endogenous HMOX1 (show HMOX1 Antibodies) gene but not the AKR1C2 gene is strongly repressed by Bach1 (show BACH1 Antibodies) in HaCaT keratinocytes.

  4. In model cell lines of endometrial cancer, AKR1C2 and SRD5A1 (show SRD5A1 Antibodies) have crucial roles in progesterone metabolism.

  5. Significantly higher levels of SRD5A1 (show SRD5A1 Antibodies), AKR1C2, AKR1C3 (show AKR1C3 Antibodies), and HSD17B10 (show HSD17B10 Antibodies) mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue

  6. The V54L mutation significantly decreases the 3alpha-hydroxysteroid dehydrogenase activity of DDH2 for the reduction of dihydrotestosterone.

  7. DDH2 expression might be a potential predictor and monitor of cisplatin efficacy in advanced NSCLC patients.

  8. Data suggest that interleukin-1beta facilitates progesterone metabolism in cervical fibroblasts by regulating expression of AKR1C1 (show DDH Antibodies) and AKR1C2.

  9. Data suggest that modulation of AKR1C2 by glucocorticoids (dexamethasone in this study) locally modifies exposure of adipose cells to endogenous androgens; thus, AKR1C2 activation/inactivation may be involved in regional fat deposition.

  10. role of AKR1C2 in the metabolism of testosterone and progesterone via the 5beta-reductase pathway.

AKR1C2 Antigen Profile

Protein Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with AKR1C2

  • aldo-keto reductase family 1, member C2 (AKR1C2) antibody
  • aldo-keto reductase family 1, member C2 (Akr1c2) antibody
  • AKR1C-pseudo antibody
  • Akr1c21 antibody
  • BABP antibody
  • DD antibody
  • DD2 antibody
  • DDH2 antibody
  • HAKRD antibody
  • HBAB antibody
  • MCDR2 antibody
  • SRXY8 antibody

Protein level used designations for AKR1C2

3-alpha-HSD3 , DD-2 , DD/BABP , aldo-keto reductase family 1 member C2 , chlordecone reductase homolog HAKRD , dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III , pseudo-chlordecone reductase , trans-1,2-dihydrobenzene-1,2-diol dehydrogenase , type II dihydrodiol dehydrogenase , 17-alpha-HSD , 17-alpha-hydroxysteroid dehydrogenase , 3(or 17)-alpha-hydroxysteroid dehydrogenase , 3-alpha-hydroxysteroid dehydrogenase , aldo-keto reductase family 1 member C21 , aldo-keto reductase family 1, member C21

GENE ID SPECIES
1646 Homo sapiens
291283 Rattus norvegicus
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