Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Proteins (AKR1B10)

AKR1B10 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Additionally we are shipping Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Antibodies (81) and Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AKR1B10 57016 O60218
Mouse AKR1B10 AKR1B10 67861  
Rat AKR1B10 AKR1B10 296972  
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Top Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 6 to 8 Days
$534.64
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$383.25
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$190.93
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

AKR1B10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

Top referenced Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Proteins

  1. Human AKR1B10 Protein expressed in Escherichia coli (E. coli) - ABIN667103 : Vorum, Liu, Madsen, Rasmussen, Honoré: Molecular cloning of a cDNA encoding human calumenin, expression in Escherichia coli and analysis of its Ca2+-binding activity. in Biochimica et biophysica acta 1998 (PubMed)
    Show all 2 references for 667103

  2. Human AKR1B10 Protein expressed in Wheat germ - ABIN1344748 : Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015 (PubMed)

More Proteins for Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) Interaction Partners

Human Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) interaction partners

  1. This study presents novel evidence that AKR1B10 protects colon cells from DNA damage induced by electrophilic carbonyl compounds.

  2. the highly efficient, retinaldehyde-specific aldo-keto reductase enzyme AKR1B10 is up-regulated in keloid epidermis(KE) and its induced overexpression in normal skin keratinocytes affects the classical RA pathway, recreating KE expression patterns

  3. Data suggest that expression of STAR (steroidogenic acute regulatory protein (show STAR Proteins)) and AKR1B10 (aldo-keto reductase family 1, member B10 (show ENPP3 Proteins)) is down-regulated in high-grade versus low-grade endometrial tumors; expression of AKR1B10 correlates with body mass index, with up-regulation of expression of AKR1B10 in obese patients with endometrial tumors.

  4. Result indicate that the differential scanning fluorimetry (DSF) method is useful for enzyme inhibitor drug screening for the AKR superfamily, including AKR1B10 and a structurally similar isoform AKR1B1 (show AKR1B1 Proteins).

  5. Chronic hepatitis C patients expressing high levels of hepatic AKR1B10 had an increased risk of HCC (show FAM126A Proteins) development even after sustained virological response

  6. Various degrees of AKR1B10 upregulation in the liver were observed in patients with chronic HCV infection, and high AKR1B10 expression could be a novel pre- dictor of HCC (show FAM126A Proteins).

  7. AKR1B10 is up-regulated with cisplatin resistance in gastrointestinal cancer cells.

  8. AKR1B10 mRNA and protein levels were higher in primary hepatocellular carcinoma (PHC (show SLC25A3 Proteins)) tissues than in peri (show PLIN1 Proteins)-tumor tissues.

  9. AKR1B10 is overexpressed in nasopharyngeal hyperplasia, benign tumors, and carcinomas, being a potential new biomarker.

  10. Even at early stages of malignant transformationa considerable increase in AKR1B10 mRNA content was observed in 80% of tumors

Mouse (Murine) Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) interaction partners

  1. Our results demonstrate that sulindac inhibits pancreatic carcinogenesis by the inhibition of Kras protein prenylation by targeting AKR1B10.

  2. AKR1B15 and Akr1b16 genes are expressed as functional proteins in human and murine tissues [Akr1b16]

Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) Protein Profile

Protein Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Gene names and symbols associated with AKR1B10

  • aldo-keto reductase family 1, member B10 (aldose reductase) (AKR1B10)
  • aldo-keto reductase family 1, member B10 (aldose reductase) (Akr1b10)
  • 2310005E10Rik protein
  • AKR protein
  • AKR1B10 protein
  • AKR1B11 protein
  • AKR1B12 protein
  • Akr1b16 protein
  • ALDRLn protein
  • ARL-1 protein
  • ARL1 protein
  • HIS protein
  • HSI protein

Protein level used designations for AKR1B10

aldo-keto reductase family 1 member B10 , aldo-keto reductase family 1, member B10 (aldose reductase) , ARP , SI reductase , aldo-keto reductase family 1, member B11 (aldose reductase-like) , aldose reductase-like 1 , aldose reductase-like peptide , aldose reductase-related protein , hARP , small intestine reductase , aldo-keto reductase family 1, member B10

GENE ID SPECIES
395338 Gallus gallus
418169 Gallus gallus
525193 Bos taurus
463867 Pan troglodytes
100585902 Nomascus leucogenys
57016 Homo sapiens
67861 Mus musculus
296972 Rattus norvegicus
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