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Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) Proteins (AOC3)

AOC3 encodes a member of the semicarbazide-sensitive amine oxidase family. Additionally we are shipping AOC3 Antibodies (95) and AOC3 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AOC3 93646 Q9Z2Q1
AOC3 8639 Q16853
AOC3 11754 O70423
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Top AOC3 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 10 to 12 Days
$86.96
Details
HOST_CHO Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$1,071.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,231.33
Details
HOST_CHO Cells Human Un-conjugated   0.002 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_CHO Cells Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$460.85
Details

AOC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , ,
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Mouse (Murine) ,
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Top referenced AOC3 Proteins

  1. Human AOC3 Protein expressed in Escherichia coli (E. coli) - ABIN2667601 : Jalkanen, Salmi: Vascular adhesion protein-1 (VAP-1)--a new adhesion molecule recruiting lymphocytes to sites of inflammation. in Research in immunology 1994 (PubMed)
    Show all 3 references for ABIN2667601

  2. Human AOC3 Protein expressed in Wheat germ - ABIN1345218 : Ma, Manaenko, Khatibi, Chen, Zhang, Tang: Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011 (PubMed)

More Proteins for Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) Interaction Partners

Human Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) interaction partners

  1. In this article, we will review the general characteristics and biological functions of VAP-1, focusing on its important role as a prognostic biomarker in human pathologies. [review]

  2. serum VAP-1 can predict ESRD and is a useful biomarker to improve risk stratification in type 2 diabetic subjects.

  3. Higher serum VAP-1 and Chronic kidney disease can independently predict future development of cancers in type II diabetic subjects

  4. Complexes of human ORP2 and VAPs at endoplasmic reticulum-lipid droplet interfaces regulate the hydrolysis of triglycerides and lipid droplet turnover.

  5. these results link the amine oxidase activity of VAP-1 with hepatic inflammation and fibrosis and suggest that targeting VAP-1 has therapeutic potential for NAFLD and other chronic fibrotic liver diseases.

  6. the semicarbazide-sensitive amine oxidase (show AOC2 Proteins) activity of VAP-1 modifies hepatic glucose homeostasis and may contribute to patterns of GLUT (show SLC2A1 Proteins) expression in chronic disease.

  7. This study demonstrated that low serum VAP-1 levels are associated with poor prognosis in gastric cancer patients.

  8. Serum VAP-1 predicts mortality independently and improves risk stratification in colorectal cancer subjects.

  9. SSAO (show AOC2 Proteins) expression in endothelial cells increases oxygen-glucose-deprivation-associated cell damage. It mediates some tissue damage during the reoxygenation process by oxidizing its known enzymatic substrate, methylamine.

  10. We concluded that VAP-1, elevated in patients on Peritoneal Dialysis, was predominantly dependent on residual kidney function and glucose level, factors both linked to endothelial damage and cardiovascular complications.

Mouse (Murine) Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) interaction partners

  1. data indicate that SSAO inactivation in vivo stabilizes the established plaques mainly via inducing the switch of SMCs from a contractile to a synthetic phenotype

  2. Suggest inhibiting VAP-1/SSAO enzymatic function, by PXS-4728A, as a novel therapeutic approach in lung diseases that are characterized by neutrophilic pattern of inflammation.

  3. these results link the amine oxidase activity of VAP-1 with hepatic inflammation and fibrosis and suggest that targeting VAP-1 has therapeutic potential for NAFLD and other chronic fibrotic liver diseases.

  4. these results suggest a largely redundant function for AOC3/VAP-1 in allergic inflammatory responses of the airways.

  5. The results of the study establish VCAM-1 (show VCAM1 Proteins) and VAP-1 as mediators of myeloid cell recruitment in metastasis and identify VAP-1 as a potential target for therapeutic intervention to combat early metastasis.

  6. The antihyperglycemic effect of benzylamine is abolished by AOC3 gene knockout in mice.

  7. Long-term activation of semicarbazide-sensitive amine oxidase by benzylamine lowers circulating levels of uric acid in diabetic conditions.

  8. AOC3 expression is increased in perigonadal and subcutaneous adipose tissue of diabetic db-/- obese mice.

  9. This review examines the biological functions of VAP-1, especially the role that this molecule might play in the establishment and progression of chronic liver disease.

  10. The demonstrated AOC3 turnover of primary amines that are non-native to human tissue suggests possible roles for the adipocyte enzyme in subcutaneous bacterial infiltration and obesity.

Cow (Bovine) Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3) interaction partners

  1. The lysine-rich protein soluble elastin (show ELN Proteins) bound to the enzyme tightly, which may have relevance to the reported roles of copper-containing quinoenzyme semicarbazide-sensitive amine oxidase in maintaining the extracellular matrix and in maturation of elastin (show ELN Proteins)

AOC3 Protein Profile

Protein Summary

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with AOC3

  • SEC31 homolog A (S. cerevisiae) (Sec31a)
  • amine oxidase, copper containing 3 (AOC3)
  • amine oxidase, copper containing 3 (Aoc3)
  • amine oxidase, copper containing 3 (vascular adhesion protein 1) (AOC3)
  • BOLAO protein
  • HPAO protein
  • Sec31l1 protein
  • SSAO protein
  • VAP-1 protein
  • VAP1 protein

Protein level used designations for AOC3

SEC31-like 1 , SEC31-like protein 1 , SEC31-related protein A , protein transport protein Sec31A , vesicle associated protein , vesicle-associated protein 1 , amine oxidase, copper containing 3 (vascular adhesion protein 1) , copper amine oxidase , membrane primary amine oxidase , placenta copper monamine oxidase , semicarbazide-sensitive amine oxidase , VAP-1 , vascular adhesion protein 1 , VP97 , copper containing amine oxidase 3 , primary amine oxidase, lung isozyme

GENE ID SPECIES
93646 Rattus norvegicus
8639 Homo sapiens
11754 Mus musculus
29473 Rattus norvegicus
281002 Bos taurus
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