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The protein encoded by AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Additionally we are shipping Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase Antibodies (40) and Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase Kits (7) and many more products for this protein.
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Human AASDHPPT Protein expressed in Escherichia coli (E. coli) - ABIN667231
Praphanphoj, Sacksteder, Gould, Thomas, Geraghty: Identification of the alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase gene, the human ortholog of the yeast LYS5 gene. in Molecular genetics and metabolism 2001
Show all 2 references for ABIN667231
Our study identifies human PPT (show PPP5C Proteins) as the FDH (show ADH5 Proteins)-modifying enzyme and supports the hypothesis that mammals utilize a single enzyme for all phosphopantetheinylation reactions.
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
, aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
, 4'-phosphopantetheinyl transferase
, LYS5 ortholog
, alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase