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Required for cytokinesis. Additionally we are shipping Anillin Kits (6) and Anillin Proteins (3) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal Anillin Primary Antibody for ICC, IF - ABIN4280671
Hjelm, Forsström, Igel, Johannesson, Stadler, Lundberg, Ponten, Sjöberg, Rockberg, Schwenk, Nilsson, Johansson, Uhlén: Generation of monospecific antibodies based on affinity capture of polyclonal antibodies. in Protein science : a publication of the Protein Society 2011
Show all 2 Pubmed References
Human Polyclonal Anillin Primary Antibody for IHC (p), IHC - ABIN250023
Oegema, Savoian, Mitchison, Field: Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. in The Journal of cell biology 2000
Human Polyclonal Anillin Primary Antibody for ELISA, WB - ABIN4280669
Hall, Todd, Hyland, McDade, Grabsch, Dattani, Hillan, Russell: The septin-binding protein anillin is overexpressed in diverse human tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005
we show that the transition from the actomyosin contractile ring to the midbody ring proceeds via a previously uncharacterized maturation process that requires opposing mechanisms of removal and retention of the scaffold protein (show HOMER1 Antibodies) Anillin.
Anillin is required for complete closure of the contractile ring and formation of the midbody ring during cytokinesis.
the anillin pleckstrin (show PLEK Antibodies) homology domain has two functions: targeting anillin to the plasma membrane furrow by binding to phosphatidylinositol phosphate lipids to maintain furrow organization and recruiting septins to the furrow.
Data suggest that Cindr and Anillin cooperate to promote intercellular bridge stability during incomplete cytokinesis in Drosophila melanogaster.
Results show that the anillin-septin and cadherin-catenin complexes can serve as alternative cassettes to promote tight physical coupling of F-actin and myosin II to the cleavage furrow and successful completion of cytokinesis.
anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis
important role for scraps in scaffolding cleavage furrow components, directly stabilizing intracellular bridges
A novel RhoGEF(Pbl)-dependent input promotes the simultaneous association of anillin with the plasma membrane, septins, and microtubules, independently of F-actin.
anillin and Peanut are involved in pseudocleavage furrow ingression in syncytial embryos, a process that is regulated by Ran
Anillin (ANLN) expression in tumor cells is correlated to poor prognosis in breast cancer patients, independent of Ki-67 (show MKI67 Antibodies) or tumor size.
ANLN expression is elevated in colorectal cancer and has a strong potential to act as a biomarker for the prognosis of colorectal cancer.
Findings indicate that miR (show MLXIP Antibodies)-497 is a potent tumor suppressor that inhibits cancer phenotypes by targeting ANLN and HSPA4L (show HSPA4L Antibodies) in NPC (show NPC1 Antibodies).
High nuclear expression of anillin (ANLN) is an independent predictor of poor disease-specific survival and it is a useful prognostic marker of urothelial carcinoma of the upper urinary tract (UCUT).
Data suggest that anillin (ANLN) could be involved in breast cancer progression and a potential target candidate in breast cancer.
Identification 4 novel and 18 known exonic ANLN variants associated with carotid intima-media thickness at bifurcation.
Anillin regulates intercellular adhesion in model human epithelia by mechanisms involving the suppression of JNK (show MAPK8 Antibodies) activity and controlling the assembly of the perijunctional cytoskeleton.
The sequestration of anillin by astral microtubules might alter the organization of cortical proteins to polarize cells for cytokinesis
these data demonstrate that a complex of p190RhoGAP (show GRLF1 Antibodies)-A and anillin modulates RhoA (show RHOA Antibodies)-GTP (show AK3 Antibodies) levels in the cytokinetic furrow to ensure progression of cytokinesis.
Identified a missense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS (show ACTN4 Antibodies). We screened 250 additional families with FSGS (show ACTN4 Antibodies) and found another variant, G618C, that segregates with disease in a second family with FSGS (show ACTN4 Antibodies).
Anillin is excluded from the cortex of first polar body, enriched in the cytokinetic ring that severs the polar body from the oocyte. In meiosis II, anillin is enriched in a cortical stripe coincident with and overlying the meiotic spindle midzone.
Results show that targeting of mDia2 (show DIAPH3 Antibodies) to the cleavage furrow requires not only its binding to RhoA (show RHOA Antibodies) but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 (show DIAPH3 Antibodies) interaction partner.
The authors propose that anillin is required for proper Rho-GTP (show AK3 Antibodies) distribution at cell-cell junctions and for maintenance of a robust apical actomyosin belt, which is required for cell-cell junction integrity.
Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (By similarity).
Actin-binding protein 8
, lethal (2) k08255
, anillin, actin binding protein (scraps homolog, Drosophila)
, anillin, actin binding protein
, actin-binding protein anillin-like
, actin-binding protein anillin
, contractile ring component anillin