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anti-Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) Antibodies

ASB2 encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. Additionally we are shipping ASB2 Kits (11) and ASB2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASB2 51676 Q96Q27
ASB2 65256 Q8K0L0
ASB2 299266 Q5U2S6
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Top anti-ASB2 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB ASB2 Antibody (N-term)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the ASB2 antibody detected the ASB2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Asb-2 using ABIN252587 at 1:1,000 dilution against 15 ug/lane of human spleen lysate (lane 1) and lung lysate (lane 2). 0.2 mL Log in to see 5 to 7 Days
$341.25
Details
Human Rabbit Un-conjugated WB 200 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ASB2 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ASB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against ASB2 Interaction Partners

Human Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) interaction partners

  1. Using ASB2 conditional knockout mice.

  2. Phosphorylation of serine 323 of ASB2 alpha by Erk (show EPHB2 Antibodies) kinases is critical for ASB2alpha-mediated degradation of FLNA (show FLNA Antibodies).

  3. data therefore reveal ubiquitin acceptor sites in FLNa (show FLNA Antibodies) and establish that ASB2alpha-mediated effects on cell spreading are due to loss of filamins.

  4. Data show that neither endogenous nor exogenously expressed ASB2alpha induces degradation of JAK (show JAK3 Antibodies) proteins in hematopoietic cells

  5. A model whereby ASB2 contributes to hematopoietic differentiation, in part, through MLL (show MLL Antibodies) degradation and HOX (show MSH2 Antibodies) gene down-regulation.

  6. By shifting monomeric E3 ligase complexes to dimeric forms through activation of Asb2 transcription, Notch (show NOTCH1 Antibodies) could effectively control the turnover of a variety of substrates and it exerts diverse effects on cell proliferation and differentiation.

  7. ASB2 may regulate hematopoietic cell differentiation by modulating cell spreading and actin remodeling through targeting of filamins A and B for degradation.

Mouse (Murine) Ankyrin Repeat and SOCS Box-Containing 2 (ASB2) interaction partners

  1. This study identifies desmin (show DES Antibodies) as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin (show DES Antibodies) could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  2. ASB2(-/-) immature dendritic cells exhibit reduced matrix-degrading function leading to defective migration.

  3. ASB2beta is part of an active E3 ubiquitin ligase (show MUL1 Antibodies) complex and targets the actin-binding protein (show PFN1 Antibodies) filamin B (show FLNB Antibodies) for proteasomal degradation.

ASB2 Antigen Profile

Protein Summary

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ASB2

  • ankyrin repeat and SOCS box containing 2 (ASB2) antibody
  • ankyrin repeat and SOCS box-containing 2 (ASB2) antibody
  • ankyrin repeat and SOCS box-containing 2 (Asb2) antibody
  • 1110008E15Rik antibody
  • ASB-2 antibody
  • ASB2 antibody

Protein level used designations for ASB2

ankyrin repeat and SOCS box-containing 2 , ankyrin repeat and SOCS box protein 2-like , ankyrin repeat and SOCS box protein 2 , ankyrin repeat and SOCS box-containing protein 2a , ASB-2 , ankyrin repeat and SOCS box-containing protein 2 , ankyrin repeat-containing SOCS box protein 2

GENE ID SPECIES
100064381 Equus caballus
423428 Gallus gallus
467538 Pan troglodytes
490836 Canis lupus familiaris
699882 Macaca mulatta
100227715 Taeniopygia guttata
100385735 Callithrix jacchus
100451651 Pongo abelii
51676 Homo sapiens
539244 Bos taurus
65256 Mus musculus
299266 Rattus norvegicus
Selected quality suppliers for anti-ASB2 (ASB2) Antibodies
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