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anti-Anthrax Toxin Receptor 2 (ANTXR2) Antibodies

ANTXR2 encodes a receptor for anthrax toxin. Additionally we are shipping ANTXR2 Proteins (18) and ANTXR2 Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANTXR2 71914 Q6DFX2
ANTXR2 118429 P58335
ANTXR2 305633  
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Top anti-ANTXR2 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB AP20115PU-N ANTXR2 antibody staining of Mouse Kidney lysate at 0.3 µg/ml (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Antxr2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Mouse Liver WB Suggested Anti-Antxr2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Mouse Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated FACS, WB Detection of CMG-2/ANTXR2 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Human CMG-2/ANTXR2 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Goat Un-conjugated ELISA, WB Western Blot: CMG-2/ANTXR2 Antibody [NBP1-49866] - Analysis of Mouse Kidney lysate (35ug protein in RIPA buffer) using this antibody at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat PE FACS Detection of CMG-2/ANTXR2 in Human Whole Blood Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CMG-2/ANTXR2 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Human Goat Allophycocyanin FACS Detection of CMG-2/ANTXR2 in Human Whole Blood Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CMG-2/ANTXR2 APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$367.50
Details
Human Goat Biotin FACS, WB Detection of CMG-2/ANTXR2 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CMG-2/ANTXR2 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Log in to see 8 to 9 Days
$399.00
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

ANTXR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ANTXR2 Antibodies

  1. Human Polyclonal ANTXR2 Primary Antibody for FACS, WB - ABIN4900575 : Friebe, Deuquet, van der Goot: Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8. in PLoS ONE 2015 (PubMed)
    Show all 4 references for ABIN4900575

  2. Cow (Bovine) Polyclonal ANTXR2 Primary Antibody for EIA, WB - ABIN498028 : Deuquet, Abrami, Difeo, Ramirez, Martignetti, van der Goot: Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. in Human mutation 2009 (PubMed)

More Antibodies against ANTXR2 Interaction Partners

Mouse (Murine) Anthrax Toxin Receptor 2 (ANTXR2) interaction partners

  1. Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 (show ANTXR1 Antibodies) Receptors for Cellular Uptake and Tumor Targeting.

  2. blood pressure measured under anesthesia in Antxr2 siRNA-injected mice rose significantly compared with that of the controls, suggesting that ANTXR2 is a causative gene in the human 4q21 GWAS-blood pressure locus.

  3. Silencing CMG2 using targeted siRNAs provided almost complete protection against anthrax lethal toxin-induced cytotoxicity and death in murine and human macrophages.

  4. we have discovered that ANTXR1 (show ANTXR1 Antibodies) and ANTXR2 function as positive regulators of MT1-MMP (show MMP14 Antibodies) activity.

  5. these results demonstrate that CMG2 is not required for normal mouse embryonic development but is indispensable for murine parturition

  6. This work demonstrates that anthrax toxin uptake through CMG2 and the resulting impairment of myeloid cells are essential to anthrax infection.

  7. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.

  8. Cytoplasmic delivery of lethal factor by anthrax toxin receptor 2 was mediated by cathepsin B (show CTSB Antibodies).

  9. because protective antigen binds to CMG2 with much higher affinity than it does to TEM8 (show ANTXR1 Antibodies), a lower pH is needed to attenuate CMG2 binding to allow pore formation; toxin can form pores at different points in the endocytic pathway

  10. The mRNA transcripts of both receptors, ANTXR1 (show ANTXR1 Antibodies) and ANTXR2 were detected in J774A.1 cells and mouse tissues suggesting that anthrax edema toxin and B. anthracis Sterne spore are involved in the ANTXR mRNA regulation in host cells.

Human Anthrax Toxin Receptor 2 (ANTXR2) interaction partners

  1. This study reports a novel association between ANTXR2 and ankylosing spondylitis in the Han Chinese.

  2. Case Report: systemic hyalinosis with a heterozygous mutation in CMG2.

  3. The association between ANTXR2 rs4333130 and ankylosing spondylitis was independent of HLA-B27 status. Clinical disease severity scores (BASDAI and BASFI) and pain score were higher in ANTXR2 rs4333130 CT genotype.

  4. Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation

  5. Anthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression

  6. miR (show MLXIP Antibodies)-124 might induce autophagy to participate in AS by targeting ANTXR2, which might be implicated in pathological process of AS.

  7. The disulfide bond Cys255-Cys279 in the immunoglobulin-like domain of ANTXR2 is required for membrane insertion of anthrax protective antigen pore.

  8. CMG2 glycosylation provides a buffer towards genetic variation by promoting folding of the protein in the ER lumen.

  9. Results show that CMG2 has been shown to be able to regulate the proliferation and tubule formation of endothelial cells, but not the migration.

  10. Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene.

ANTXR2 Antigen Profile

Protein Summary

This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ANTXR2

  • anthrax toxin receptor 2 (ANTXR2) antibody
  • anthrax toxin receptor 2 (antxr2) antibody
  • anthrax toxin receptor 2 (Antxr2) antibody
  • 2310046B19Rik antibody
  • ANTXR2 antibody
  • AW561899 antibody
  • cI-35 antibody
  • CMG-2 antibody
  • CMG2 antibody
  • DKFZp459A152 antibody
  • HFS antibody
  • ISH antibody
  • JHF antibody

Protein level used designations for ANTXR2

anthrax toxin receptor 2 , capillary morphogenesis gene 2 protein , capillary morphogenesis protein 2

GENE ID SPECIES
422580 Gallus gallus
471191 Pan troglodytes
696513 Macaca mulatta
100051770 Equus caballus
100158556 Xenopus (Silurana) tropicalis
100174746 Pongo abelii
100356899 Oryctolagus cuniculus
100582046 Nomascus leucogenys
71914 Mus musculus
118429 Homo sapiens
487821 Canis lupus familiaris
510080 Bos taurus
305633 Rattus norvegicus
100514416 Sus scrofa
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