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Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. Additionally we are shipping APOA4 Antibodies (162) and APOA4 Kits (46) and many more products for this protein.
Showing 10 out of 27 products:
Upregulation of the intestinal apolipoprotein APOA-IV in horses with chronic laminitis was confirmed by western blot.[APOA-IV]
zebrafish ApoA-IV performs a conserved role to that in rat in the regulation of food intake by transiently overexpressing ApoA (show APOA1 Proteins)-IVb.
Low levels of APOA1 (show APOA1 Proteins), APOC3 (show APOC3 Proteins), and APOA4 are associated with risk of Alzheimer disease.
Single nucleotide polymorphisms (Rs7396835) of APOA4 protein did not increase the risk of CHD (show CHDH Proteins) in the Chinese population.
ApoA-IV colocalizes with NR4A1 (show NR4A1 Proteins), which suppresses G6Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.
the present findings reveal that High-altitude polycythemia -induced gastric mucosal lesion inspires the protection responses by up-regulating APOA4 and APOC3 (show APOC3 Proteins), and down-regulating GIF (show GIF Proteins).
analysis of methylation patterns of the APOA1 (show APOA1 Proteins)/C3/A4/A5 cluster that may be directly involved in the transcriptional regulation of this cluster, especially in liver
the systematic conversion of conserved prolines to alanine increased the thermodynamic stability of apoA-IV and its propensity to oligomerize
transcriptional regulation of apolipoprotein A-IV by the transcription factor CREBH (show CREB3L3 Proteins)
The structure of human apolipoprotein A-IV as revealed by stable isotope-assisted cross-linking, molecular dynamics, and small angle x-ray scattering.
apoA-IV inhibits hepatic gluconeogenesis by decreasing Glc-6-Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression through NR1D1 (show NR1D1 Proteins).
apoA-IV was increased in follicular fluid from polycystic ovary syndrome patients compared with those from normal controls
It was suggested that increased ileal GPR119 (show GPR119 Proteins) is a potential mechanism by which GLP-1 (show GCG Proteins) secretion is enhanced in apoA-IV-/- mice.
these data suggest that apoA-IV is not necessary for the metabolic improvements shown with VSG, but also suggest an interesting role for apoA-IV in regulating macronutrient preference and hepatic triglyceride levels.
These results reveal ApoA-IV as a novel follicle-associated epithelium-specific marker especially in the upper small intestine of adult mice.
Hepatic steatosis in mice induces hepatic apoA-IV expression, which in turn promotes lipoprotein particle expansion and reduces hepatic lipid burden without increasing the number of secreted atherogenic apoB (show APOB Proteins)-containing lipoprotein particles.
Data indicate that plasma lipids, lipid absorption, and microsomal triglyceride transfer protein (MTP (show MTTP Proteins)), FoxO1 (show FOXO1 Proteins), and FoxA2 (show FOXA2 Proteins) levels are lower at night and at mealtime in apoAIV-/- mice.
a novel function of apoA-IV in the biogenesis of discrete HDL (show HSD11B1 Proteins)-A-IV particles with the participation of ABCA1 (show ABCA1 Proteins) and LCAT (show LCAT Proteins)
peripheral apo AIV requires an intact CCK (show CCK Proteins) system and vagal afferents to activate neurons in the hindbrain to reduce food intake
results suggest that apoA-IV may provide a therapeutic target for the regulation of glucose-stimulated insulin (show INS Proteins) secretion and treatment of diabetes
MTTP (show MTTP Proteins) is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption.
down-regulation of apolipoprotein A-I (show APOA1 Proteins) and A-IV messages in the liver may be mediated by interleukin 6 (show IL6 Proteins) and tumor necrosis factor-alpha (show TNF Proteins)
Hepatocyte nuclear factor 4 alpha (HNF-4 alpha (show HNF4A Proteins))induces apoliprotein IV gene in response to dietary lipids in the intestine.
APOA4 genes with SNPs
Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.
, apolipoprotein A-IV
, apolipoprotein A4
, apolipoprotein A-IV-like