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Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B Proteins (APOBEC3B)

APOBEC3B is a member of the cytidine deaminase gene family. Additionally we are shipping APOBEC3B Antibodies (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOBEC3B 9582 Q9UH17
APOBEC3B 315137  
APOBEC3B    
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Top APOBEC3B Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cricetulus longicaudatus His tag   1 mg Log in to see 56 to 66 Days
$3,094.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,197.33
Details

APOBEC3B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Cricetulus longicaudatus

More Proteins for Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) Interaction Partners

Human Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) interaction partners

  1. Data indicate that SIVmac239 Vif (show BTG1 Proteins) protein efficiently degrades human DNA cytosine deaminase APOBEC3B protein (huA3B).

  2. Data show that restriction factor APOBEC3G (show APOBEC3G Proteins) (A3G) is susceptible to degradation by the HIV-1 Vif (show BTG1 Proteins) protein, whereas restriction factor APOBEC3B (A3B (show SGCB Proteins)) is resistant to Vif (show BTG1 Proteins).

  3. APOBEC3B is required for regulation of gene expression by ERalpha (show ESR1 Proteins) and acts by causing C-to-U deamination at ERalpha (show ESR1 Proteins) binding regions.

  4. These results suggest that functional potential of APOBEC3B and APOBEC3C (show APOBEC3C Proteins) involved in cancer mutagenesis is associated with estrogen receptor (show ESR1 Proteins) status.

  5. The APOBEC3B deletion polymorphism was found to be associated with HBV, HCV, TTV (show EXT1 Proteins), and T. gondii co-infection in Indonesian HIV-infected individuals.

  6. Germline variant and deletion polymorphism in APOBEC3B gene are not associated with breast cancer risk.

  7. APOBEC3B expression was correlated with unfavorable prognosis in patients with gastric cancer.

  8. APOBEC3B expression is an independent predictor of recurrence in patients with ccRCC, and the prognostic value is most prominent in those with low-risk disease.

  9. report the first structures of the APOBEC3B catalytic domain in multiple crystal forms. These structures reveal a tightly closed active site conformation and suggest that substrate accessibility is regulated by adjacent flexible loops

  10. APOBEC3B overexpression and Fhit-loss induced DNA damage are independent events that, when occurring together, result in a significantly increased frequency of APOBEC-induced mutations that drive cancer progression.

APOBEC3B Protein Profile

Protein Summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with APOBEC3B

  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (APOBEC3B)
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (Apobec3b)
  • A3B protein
  • APOBEC1L protein
  • Apobec3 protein
  • APOBEC3B protein
  • Apobec3f protein
  • APOBEC3H protein
  • APOBEC3Z2 protein
  • APOBEC3Z3 protein
  • ARCD3 protein
  • ARP4 protein
  • bK150C2.2 protein
  • DJ742C19.2 protein
  • PHRBNL protein

Protein level used designations for APOBEC3B

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D , probable DNA dC->dU-editing enzyme APOBEC-3B , apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B , DNA dC->dU-editing enzyme APOBEC-3B , cytidine deaminase , phorbolin 2 , phorbolin 3 , phorbolin-1-related protein , phorbolin-2/3 , apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F , DNA dC->dU-editing enzyme APOBEC3 , apolipoprotein B editing complex 3 , probable DNA dC->dU-editing enzyme APOBEC3

GENE ID SPECIES
481248 Canis lupus familiaris
743891 Pan troglodytes
100628312 Macaca mulatta
9582 Homo sapiens
504505 Bos taurus
315137 Rattus norvegicus
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