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Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. Additionally we are shipping APOH Kits (62) and APOH Proteins (36) and many more products for this protein.
Showing 10 out of 148 products:
Human Monoclonal APOH Primary Antibody for WB - ABIN395997
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN395997
Human Monoclonal APOH Primary Antibody for IHC (fro), WB - ABIN119572
Chamley, Konarkowska, Duncalf, Mitchell, Johnson: Is interleukin-3 important in antiphospholipid antibody-mediated pregnancy failure? in Fertility and sterility 2001
Show all 2 references for ABIN119572
Human Polyclonal APOH Primary Antibody for WB - ABIN513421
Mulla, Brosens, Chamley, Giles, Pericleous, Rahman, Joyce, Panda, Paidas, Abrahams: Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. in American journal of reproductive immunology (New York, N.Y. : 1989) 2009
Human Polyclonal APOH Primary Antibody for ELISA, WB - ABIN4281229
Hirose, Williams, Alberts, Furie, Chartash, Jain, Sison, Lahita, Merrill, Cucurull, Gharavi, Sammaritano, Salmon, Hashimoto, Sawada, Chu, Gregersen, Chiorazzi: A role for the polymorphism at position 247 of the beta2-glycoprotein I gene in the generation of anti-beta2-glycoprotein I antibodies in the antiphospholipid syndrome. in Arthritis and rheumatism 1999
Human Polyclonal APOH Primary Antibody for IHC, IHC (p) - ABIN4281227
Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011
Cow (Bovine) Polyclonal APOH Primary Antibody for WB - ABIN2784436
Fischetti, Durigutto, Pellis, Debeus, Macor, Bulla, Bossi, Ziller, Sblattero, Meroni, Tedesco: Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor. in Blood 2005
These results suggested that CRP (show CRP Antibodies)/oxidized low density lipoprotein/beta 2-Glycoprotein I complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK (show MAPK14 Antibodies) and NFkappaB signaling pathways.
TLR2 (show TLR2 Antibodies) increase the stimulating effect of beta2GP1/anti-beta2GP1 complex on the expression of TNF-alpha (show TNF Antibodies) in mouse peritoneal macrophages
The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury.
These results indicate that both NF-kappaB (show NFKB1 Antibodies) and c-Jun/AP-1 (show JUN Antibodies) are involved in regulating anti-beta2GPI-induced expression of prothrombotic and proinflammatory molecules in vivo.
Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.
beta2-GPI-D-I-tDCs may offer a novel approach for developing therapy for APS (show SH2B2 Antibodies) patients
Deletion of beta2 GPI accelerates and potentiates the autoimmune phenotype in male BXSB.Yaa mice
Interaction of beta2-glycoprotein I with lipopolysaccharide leads to Toll-like receptor 4 (TLR4 (show TLR4 Antibodies))-dependent activation of macrophages
Data are consistent with pathogenic mechanisms in antiphospholipid syndrome involving both neutralization of beta(2)-glycoprotein I (beta(2)GPI) function and beta(2)GPI-immunoglobulin complex formation.
beta-2-glycoprotein 1 plays an important physiologic role in the recognition of dying cells
Pretransplant IgA-aB2GP1 was the main risk factor for graft thrombosis and early graft loss after renal transplantation.
These results suggest that antibodies directed against domain 1 of beta-2-glycoprotein 1 may contribute to antiphospholipid syndrome risk assessment, due to their association with the diagnosis of systemic autoimmunity and with more aggressive triple antiphospholipid antibody profiles, such as triple positivity and lupus anticoagulant activity.
Circulating Immune Complexes of IgA Bound to Beta 2 Glycoprotein are Strongly Associated with the Occurrence of Acute Thrombotic Events.
Genome-wide significant results in or near the APOH gene on chromosome 17 have been found for plasma apolipoprotein H levels in middle-aged and older adults.
Prevalence and pathogenicity of IgA aB2GPI antibodies may vary from a population of ESRD patients to another.
The association of IL28B (show IL28B Antibodies) and APOH single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA (show ITPA Antibodies) SNPs with anemia related phenotypes.
We identified APOH as an obesity-resistance gene that interacts with FTO (show FTO Antibodies) rs9939609 to more than double the occurrence of thinness.
Trp316Ser variant (rs1801690) near the apolipoprotein H (beta2-glycoprotein-I) gene was associated with serum lipid parameters in Chinese volunteers. Suggest that there may be have racial/ethnic-and/or gender-specificity.
Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitor-based therapy.
The renoprotective and antifibrosis effects of beta2GPI and reduced beta2GPI on diabetic nephropathy were closely associated with suppressing the activation of the TGF-beta1 (show TGFB1 Antibodies)-p38 MAPK (show MAPK14 Antibodies) pathway.
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
, apolipoprotein H (beta-2-glycoprotein I)
, APC inhibitor
, activated protein C-binding protein
, beta-2-glycoprotein 1
, beta-2-glycoprotein I
, anticardiolipin cofactor