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Apolipoprotein L, 1 Proteins (APOL1)

APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Antibodies (108) and APOL1 Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOL1 8542 O14791
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Top APOL1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

APOL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,

More Proteins for Apolipoprotein L, 1 (APOL1) Interaction Partners

Human Apolipoprotein L, 1 (APOL1) interaction partners

  1. We examined whether APOL1 G1 and G2 renal-risk variant serum concentrations or lipoprotein distributions differed from nonrisk G0 APOL1 in African Americans without nephropathy.

  2. Sociodemographic factors and common risk factors for chronic kidney disease progression do not seem to alter APOL1-related CKD progression.

  3. APOL1 G1 and G2 genotypes in deceased African American liver donors have minimal effects on liver transplant outcomes.

  4. blacks with two APOL1 risk alleles had the highest risk for albuminuria and eGFRcys decline in young adulthood, whereas disparities between low-risk blacks and whites were related to differences in traditional risk factors.

  5. we have shown that individuals with the high risk APOL1 genotype enrolled in the NEPTUNE (show KLF17 Proteins) study present, from a clinical and histologic perspective, with more advanced disease and have less remission of proteinuria over time.

  6. Only APOL1 G1 and G2 confer renal risk, and other common and rare APOL1 missense variants, including the archaic G3 haplotype, do not contribute to sporadic FSGS (show ACTN4 Proteins) and HIVAN in the US population.

  7. Expression of either G1 or G2 APOL1 variants increased cell swelling and death vs G0-expressing cells. This was preceded by G1 or G2 APOL1-induced net efflux of intracellular potassium, resulting in the activation of stress-activated protein kinases.

  8. APOL1 genotype is associated with albuminuria, subclinical atherosclerosis, incident myocardial infarction, and mortality in older African Americans.

  9. This review provides an update on the biological functions for circulating (trypanosome resistance) and intracellular (emerging role for autophagy) APOL1.

  10. Higher levels of factor VIIc, VIIIc (show COX7A1 Proteins), fibrinogen, vonWillebrand factor, and protein C were associated with ESRD risk, with a significantly stronger association of factor VIIIc (show COX7A1 Proteins) and protein C in African Americans with two APOL1 risk alleles.

APOL1 Protein Profile

Protein Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Apolipoprotein L, 1 Proteins (APOL1)

  • apolipoprotein L, 1 (apol1)
  • apolipoprotein L, 1 (APOL1)
  • APO-L protein
  • APOL protein
  • APOL-I protein
  • FSGS4 protein
  • si:rp71-1g18.12 protein
  • wu:fa95b12 protein
  • wu:fc30h04 protein

Protein level used designations for Apolipoprotein L, 1 Proteins (APOL1)

apolipoprotein L1

GENE ID SPECIES
560340 Danio rerio
8542 Homo sapiens
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