Arachidonate 15-Lipoxygenase B (ALOX15B) ELISA Kits

ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. Additionally we are shipping Arachidonate 15-Lipoxygenase B Antibodies (70) and Arachidonate 15-Lipoxygenase B Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ALOX15B 247 O15296
ALOX15B 266604 Q8K4F2
ALOX15B 11688 O35936
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Top Arachidonate 15-Lipoxygenase B ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
Details
Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
Details

More ELISA Kits for Arachidonate 15-Lipoxygenase B Interaction Partners

Human Arachidonate 15-Lipoxygenase B (ALOX15B) interaction partners

  1. Ca(2 (show CA2 ELISA Kits)+) binding induces major structural changes in the 15-lipoxygenase-2 PLAT (show PLAT ELISA Kits) domain.

  2. 15-LOX-2 is distributed at the plasma membrane when cells are stimulated by the addition Ca(2 (show CA2 ELISA Kits)+) ionophore and that cellular localization is dependent upon the presence of a putative membrane insertion loop.

  3. these results demonstrate the strict regiospecificity of h15-LOX-2 (show ALOX5 ELISA Kits) that circumscribes its role in transcellular synthesis.

  4. This study combined molecular dynamics simulations, QM/MM calculations, and umbrella sampling free energy simulations to study the hydrogen atom abstraction from arachidonic acid catalyzed by the human enzyme 15-lipoxygenase-2.

  5. The ALOX15B gene may be associated with coronary artery disease.

  6. ALOX15 (show ALOX15 ELISA Kits) rs11568070 polymorphisms did not discriminate for the disease or its severity.

  7. 15-LOX2 expression inhibits Myc (show MYC ELISA Kits)-induced prostate cancer development, such that in the 3-month- and 6-month-old double transgenic mice, there is a significant reduction in prostate intraneoplasia.

  8. activated ALOX15B in macrophages may play a role in the induction of atherothrombotic events by increasing platelet aggregation and thrombin (show F2 ELISA Kits) generation

  9. Positive feedback-loop of TERT (show TERT ELISA Kits) and 15-lipoxygenase-2 promotes pulmonary hypertension.

  10. Presented is the crystal structure of 15-LOX-2 in complex with an inhibitor that appears to bind as a substrate mimic. 15-LOX-2 contains a long loop, composed of hydrophobic amino acids, which projects from the amino-terminal membrane-binding domain.

Mouse (Murine) Arachidonate 15-Lipoxygenase B (ALOX15B) interaction partners

  1. 15-LOX-2 is distributed at the plasma membrane when cells are stimulated by the addition Ca(2 (show CA2 ELISA Kits)+) ionophore and that cellular localization is dependent upon the presence of a putative membrane insertion loop.

  2. Knockdown of mouse Alox15b in vivo decreased plaque lipid content and markers of inflammation.

  3. 15-LOX2 expression in mouse prostate leads to hyperplasia and also induces cell senescence.

  4. 8S-LOX plays a role as a prodifferentiating, antitumorigenic, and tumor suppressing gene in mouse skin carcinogenesis.

  5. Purified recombinant 8S-lipoxygenase can function as a potential 15-LOX (show ALOX15 ELISA Kits) by converting arachidonic acid exclusively to 8S-HPETE and then to (8S,15S)-dihydroperoxy-5Z,9E,11Z,13E-eicosatetraenoic acid (8S,15S-diHPETE).

  6. Expression of 8S-LOX and 15S-LOX-2 (show ALOX5 ELISA Kits) suppresses CRD-BP/IMP-1 (show IGF2BP1 ELISA Kits) expression, resulting in inhibition of human prostate carcinoma PC-3 (show PCSK1 ELISA Kits) cell proliferation.

Arachidonate 15-Lipoxygenase B (ALOX15B) Antigen Profile

Antigen Summary

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with ALOX15B

  • arachidonate 15-lipoxygenase, type B (ALOX15B) antibody
  • arachidonate 15-lipoxygenase, type B (Alox15b) antibody
  • arachidonate 8-lipoxygenase (Alox8) antibody
  • 8-LOX antibody
  • 8S-LOX antibody
  • 15-LOX-2 antibody
  • 15-LOX-B antibody
  • Alox15b antibody

Protein level used designations for ALOX15B

arachidonate 15-lipoxygenase, type B , arachidonate 15-lipoxygenase, second type , 15-LOX-B , 15S-lipoxygenase , arachidonate 15-lipoxygenase 2 , arachidonate 15-lipoxygenase B , arachidonate 15-lipoxygenase type II , arachidonate omega(6) lipoxygenase , 15-LOX-2 , 15-lipoxygenase 2 , 8S-lipoxygenase

GENE ID SPECIES
716764 Macaca mulatta
100073039 Equus caballus
455104 Pan troglodytes
247 Homo sapiens
489485 Canis lupus familiaris
286820 Bos taurus
266604 Rattus norvegicus
100525835 Sus scrofa
11688 Mus musculus
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