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Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 Proteins (ARNTL2)

ARNTL2 encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. Additionally we are shipping ARNTL2 Antibodies (43) and ARNTL2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ARNTL2 ARNTL2 170903  
ARNTL2 56938 Q8WYA1
ARNTL2 272322 Q2VPD4
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Top ARNTL2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ARNTL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) Interaction Partners

Human Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) interaction partners

  1. BMAL2 rs7958822 genotype is associated with type 2 diabetes in obese men and women; an interaction between BMAL2 rs7958822 genotype and obesity was observed in men

  2. The prevalence of C carriers in BMAL2 gene rs2306074 T/C in Alzheimer disease patients was significantly higher than that of control subjects

  3. there is significant association between diurnal preference and a polymorphism in PER3 and a novel nominally significant association between diurnal preference and a polymorphism in ARNTL2

  4. ARNTL2 expression is increased in colorectal cancer and in a highly proliferative colon cancer cell line and is related to tumor invasiveness and aggressiveness.

  5. results show a difference in the expression pattern of Bmal2, but not Clock and Dec1 (show BHLHE40 Proteins) in PD.

  6. Alternative splicing yields novel BMAL2 variants: tissue distribution and functional characterization.

  7. Several new polymorphisms in ARNTL2 are reported.

  8. PER2 (show PER2 Proteins) is inhibited by BMAL2-CLOCK, which reemphasizes its negative role and a positive role of BMAL2 in circadian transcription

Mouse (Murine) Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) interaction partners

  1. Our results describe a novel and rather unexpected role for Arntl2 in the immune system that lies outside of its predicted function in circadian rhythm regulation

  2. Results provide additional support for the protective role of the Arntl2 gene located in locus Idd6 in diabetes progression in NOD.C3H congenic mice.

  3. Expression of Bmal2 can rescue the clock and metabolic phenotypes of Bmal1 (show ARNTL Proteins)-knockout mice, including rhythmic locomotor activity, rhythmic metabolism, low body weight, and enhanced fat deposition.

  4. These findings demonstrate that (57)Arg in the basic region of DEC2 (show BHLHE41 Proteins) is essential for its activity in suppressing CLOCK/BMAL2-mediated transactivation.

  5. Arntl2 exhibited a six-fold upregulation in spleens of the NOD.C3H 6.VIII (show COX8A Proteins) congenic strain compared with the NOD control strain, strain-specific splice variants and a large number of polymorphisms in both coding and non-coding regions.

  6. PER2 (show PER2 Proteins) is inhibited by BMAL2-CLOCK, which reemphasizes its negative role and a positive role of BMAL2 in circadian transcription

ARNTL2 Protein Profile

Protein Summary

This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ARNTL2

  • aryl hydrocarbon receptor nuclear translocator-like 2 (arntl2)
  • aryl hydrocarbon receptor nuclear translocator-like 2 (Arntl2)
  • aryl hydrocarbon receptor nuclear translocator-like 2 (ARNTL2)
  • aryl hydrocarbon receptor nuclear translocator-like 2 (LOC100224038)
  • aryl hydrocarbon receptor nuclear translocator-like 2 (LOC100355370)
  • 4632430A05Rik protein
  • Arnt4 protein
  • ARNTL2 protein
  • bHLHe6 protein
  • BMAL2 protein
  • CLIF protein
  • MOP9 protein
  • PASD9 protein
  • wu:fj90c09 protein

Protein level used designations for ARNTL2

aryl hydrocarbon receptor nuclear translocator-like protein 2 , bmal2a , brain and muscle ARNT-like 2 , aryl hydrocarbon receptor nuclear translocator-like 2 , transcription factor BMAL2 , aryl hydrocarbon receptor nuclear translocator-like protein 2-like , CYCLE-like factor , PAS domain-containing protein 9 , basic-helix-loop-helix-PAS protein MOP9 , class E basic helix-loop-helix protein 6 , member of PAS protein 9 , cBMAL2 , brain-muscle-ARNT-like protein 2 , brain and muscle Arnt-like protein 2 variant d

GENE ID SPECIES
58099 Danio rerio
170903 Rattus norvegicus
465358 Pan troglodytes
486624 Canis lupus familiaris
535794 Bos taurus
100069111 Equus caballus
100224038 Taeniopygia guttata
100355370 Oryctolagus cuniculus
100438406 Pongo abelii
100479152 Ailuropoda melanoleuca
100601744 Nomascus leucogenys
56938 Homo sapiens
373925 Gallus gallus
272322 Mus musculus
362464 Rattus norvegicus
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