Arylacetamide Deacetylase (Esterase) Proteins (AADAC)

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008].. Additionally we are shipping Arylacetamide Deacetylase (Esterase) Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AADAC 13 P22760
AADAC 57300 Q9QZH8
AADAC 67758 Q99PG0
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Top Arylacetamide Deacetylase (Esterase) Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,102.00
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Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days
$3,102.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,103.83
Details

AADAC Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Arylacetamide Deacetylase (Esterase) (AADAC) Interaction Partners

Human Arylacetamide Deacetylase (Esterase) (AADAC) interaction partners

  1. Data suggest that metabolism (and possibly pharmacokinetics) of hypnotic nitrazepam involves liver enzymes AOX1 (aldehyde oxidase 1 (show AOX1 Proteins)), NAT2 (N-acetyltransferase 2 (show NAT2 Proteins)), AADAC (arylacetamide deacetylase), and CYP3A4 (cytochrome P450 3A4 (show CYP3A4 Proteins)).

  2. Data suggest that AADAC in hepatocyte microsomes hydrolyzes ketoconazole, a synthetic imidazole antifungal agent, to N-deacetyl ketoconazole and thus triggers hepatocellular toxicity.

  3. AADAC deletion is a candidate susceptibility factor for Gilles de la Tourette Syndrome

  4. Translational N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.

  5. Lipolysis of cellular TG and VLDL production were impaired in HCV infected cells during the early peak of viral infection. This was partially explained by an apparent deficiency of a putative TG lipase (show LIPG Proteins), arylacetamide deacetylase (AADAC).

  6. An AADAC*3 allele yields decreased enzyme activity in liver microsomes.

  7. human AADAC was the enzyme responsible for the deacetylation of rifamycins and would affect the induction rate of drug-metabolizing enzymes by rifamycins and their induced hepatotoxicity.

  8. two intrinsic endoplasmic reticulum (ER) proteins, 11beta-hydroxysteroid dehydrogenase, isozyme 1 (11beta-HSD (show CHST3 Proteins)) and the 50-kDa esterase (show ESD Proteins) (E3), sharing some amino acid sequence motifs in their N-terminal transmembrane (TM) domains.

Mouse (Murine) Arylacetamide Deacetylase (Esterase) (AADAC) interaction partners

  1. Expression of AADA cDNA in McArdle-RH7777 cells significantly reduced intracellular triacylglycerol levels and apolipoprotein B (show APOB Proteins) secretion and increased fatty acid oxidation.

Arylacetamide Deacetylase (Esterase) (AADAC) Protein Profile

Protein Summary

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens

Gene names and symbols associated with AADAC

  • arylacetamide deacetylase (AADAC)
  • arylacetamide deacetylase (esterase) (aadac)
  • arylacetamide deacetylase (esterase) (AADAC)
  • Arylacetamide deacetylase (ACD3)
  • arylacetamide deacetylase (PTRG_10278)
  • Arylacetamide deacetylase (aaad)
  • arylacetamide deacetylase-like 2 (AADACL2)
  • arylacetamide deacetylase (Aadac)
  • arylacetamide deacetylase (esterase) (Aadac)
  • 5033417E09Rik protein
  • Aada protein
  • AADAC protein
  • AI265437 protein
  • CES5A1 protein
  • DAC protein
  • MGC89272 protein

Protein level used designations for AADAC

arylacetamide deacetylase (esterase) , arylacetamide deacetylase-like , Arylacetamide deacetylase , arylacetamide deacetylase , arylacetamide deacetylase-like 2

GENE ID SPECIES
100056411 Equus caballus
448381 Xenopus (Silurana) tropicalis
460785 Pan troglodytes
100126645 Xenopus laevis
100393374 Callithrix jacchus
100451808 Pongo abelii
4836710 Scheffersomyces stipitis CBS 6054
6348579 Pyrenophora tritici-repentis Pt-1C-BFP
100195711 Salmo salar
425034 Gallus gallus
13 Homo sapiens
477115 Canis lupus familiaris
57300 Rattus norvegicus
519557 Bos taurus
67758 Mus musculus
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