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AADAC Products

(Arylacetamide Deacetylase (Esterase) (AADAC))

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Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008].

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Featured AADAC Categories

AADAC Antibodies

High quality antibodies with extensive validation data.

AADAC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our AADAC products

Muta, Fukami, Nakajima, Yokoi: "N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity." in: Biochemical pharmacology, Vol. 87, Issue 2, pp. 352-9, (2014) (PubMed).

Kobayashi, Fukami, Nakajima, Watanabe, Nakajima, Yokoi: "Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 4, pp. 671-9, (2012) (PubMed).

Shimizu, Fukami, Kobayashi, Takamiya, Aoki, Nakajima, Yokoi: "A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 6, pp. 1183-90, (2012) (PubMed).

Kobayashi, Fukami, Higuchi, Nakajima, Yokoi: "Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia." in: Biochemical pharmacology, Vol. 84, Issue 9, pp. 1196-206, (2012) (PubMed).

Watanabe, Fukami, Nakajima, Takamiya, Aoki, Yokoi: "Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 7, pp. 1513-20, (2009) (PubMed).

Synonyms and alternative names related to AADAC

arylacetamide deacetylase (LOC100056411), arylacetamide deacetylase (aadac), arylacetamide deacetylase (AADAC), arylacetamide deacetylase S homeolog (aadac.S), arylacetamide deacetylase (LOC100451808), Arylacetamide deacetylase (ACD3), arylacetamide deacetylase (PTRG_10278), Arylacetamide deacetylase (aaad), arylacetamide deacetylase (Aadac), arylacetamide deacetylase (esterase) (AADAC), 5033417E09Rik, Aada, AADAC, AI265437, CES5A1, DAC, MGC89272

Protein level used designations for AADAC

  • arylacetamide deacetylase (esterase)
  • arylacetamide deacetylase-like
  • Arylacetamide deacetylase
  • arylacetamide deacetylase
  • arylacetamide deacetylase-like 2
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