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anti-Autocrine Motility Factor Receptor (AMFR) Antibodies

This locus encodes a glycosylated transmembrane receptor. Additionally we are shipping AMFR Kits (4) and AMFR Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AMFR 23802 Q9R049
AMFR 267 Q9UKV5
AMFR 361367  
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Top anti-AMFR Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AMFR Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of AMFR (arrow) using AMFR Antibody (N-term) (ABIN388938). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AMFR gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB AMFR Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB AMFR Antibody (Center)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the AMFR antibody detected the AMFR protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB AMFR antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details

AMFR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Human , ,
,
,
, , , , ,
Rat (Rattus)


Top referenced anti-AMFR Antibodies

  1. Human Polyclonal AMFR Primary Antibody for EIA, WB - ABIN950395 : Joshi, Li, Nabi: A role for KAI1 in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN950395

  2. Human Polyclonal AMFR Primary Antibody for FACS, IHC (p) - ABIN388938 : Huang, Xie, Raz: Identification of an upstream region that controls the transcription of the human autocrine motility factor receptor. in Biochemical and biophysical research communications 1995 (PubMed)
    Show all 3 references for ABIN388938

  3. Human Polyclonal AMFR Primary Antibody for EIA, IHC (p) - ABIN357584 : Araki, Shimura, Yajima, Tsutsumi, Suzuki, Okada, Kobayashi, Raz, Kuwano: Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN357584

  4. Cow (Bovine) Polyclonal AMFR Primary Antibody for WB - ABIN2775669 : Lehner, Sanderson: A protein interaction framework for human mRNA degradation. in Genome research 2004 (PubMed)

More Antibodies against AMFR Interaction Partners

Zebrafish Autocrine Motility Factor Receptor (AMFR) interaction partners

  1. gp78 plays a critical role in protecting against ER stress in liver

Mouse (Murine) Autocrine Motility Factor Receptor (AMFR) interaction partners

  1. Gp78, an E3 ubiquitin ligase (show MUL1 Antibodies) acts as a gatekeeper suppressing nonalcoholic steatohepatitis (NASH (show SAMSN1 Antibodies)) and liver cancer.

  2. The ubiquitin ligase (show RNF123 Antibodies) gp78, known for its role in protein quality control, is critical for unglycosylated PrP ubiquitylation and degradation.

  3. we consistently observe involvement of gp78 in Insig-1 (show INSIG1 Antibodies) degradation, we find no substantive evidence to support roles for either gp78 or TRC8 (show RNF139 Antibodies) in the robust sterol-accelerated degradation of HMG-CoA reductase (show HMGCR Antibodies)

  4. Ablation of gp78 in liver improves hyperlipidemia and insulin (show INS Antibodies) resistance by inhibiting SREBP to decrease lipid biosynthesis.

  5. Palmitoylation of RING finger (show PCGF1 Antibodies) cysteines therefore regulates gp78 distribution to the peripheral ER

  6. AMFR is involved in the process of learning and memory in the central nervous system.

  7. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase

  8. Gp78 promotes SOD1 (show SOD1 Antibodies) and ataxin-3 (show ATXN3 Antibodies) degradation in endoplasmic reticulum.

  9. cytoplasmic protein (show BLZF1 Antibodies) mouse p97 (show EIF4G2 Antibodies)(mp97) participates in the formation of a ternary complex containing mouse autocrine motility factor receptor (mAMFR), mp97, and peptide N-glycanase

  10. the receptor molecule for AMF/NLK/MF in leukemic differentiation is not gp78

Human Autocrine Motility Factor Receptor (AMFR) interaction partners

  1. Authors conclude that the Hrd1 (show SYVN1 Antibodies) complex forms an essential retrotranslocation module that is evolutionarily conserved, but the mammalian ERAD system uses additional ubiquitin ligases to assist Hrd1 (show SYVN1 Antibodies) during retrotranslocation.

  2. Downregulation of AMFR induced cell cycle arrest at the G0/G1 phase, and increased apoptosis of the THP1 (show GLI2 Antibodies) cells.

  3. The authors identify USP13 (show USP13 Antibodies) as a gp78-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A (show UBL4A Antibodies) to maintain the functionality of Bag6 (show BAT3 Antibodies).

  4. Data show that autocrine motility factor receptor (AMFR) and NOTCH1 (show NOTCH1 Antibodies) protein are the direct target genes of microRNA miR (show MLXIP Antibodies)-139-5p in colorectal cancer (CRC (show CALR Antibodies)).

  5. gp78 elongates polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains.

  6. Our data uncovers a previously unknown functional link between gp78 and TRIM25 (show TRIM25 Antibodies) and provides mechanistic insight into gp78-mediated protein ubiquitylation.

  7. The ubiquitin ligase gp78, known for its role in protein quality control, is critical for unglycosylated PrP (show C4BPA Antibodies) ubiquitylation and degradation.

  8. High AMFR expression is associated with invasion depth and lymph node metastasis in gastric cancer.

  9. DGAT2 (show DGAT2 Antibodies) is regulated by gp78-associated endoplasmic-reticulum-associated degradation at the post-translational level.

  10. gp78 is expressed specifically in human prostate cancer rather than normal prostate tissues, it could be a putative biomarker for prostate cancer diagnosis.

AMFR Antigen Profile

Protein Summary

This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.

Gene names and symbols associated with AMFR

  • autocrine motility factor receptor (AMFR) antibody
  • autocrine motility factor receptor, E3 ubiquitin protein ligase (amfr) antibody
  • autocrine motility factor receptor, E3 ubiquitin protein ligase (AMFR) antibody
  • autocrine motility factor receptor, amfr (AaeL_AAEL005881) antibody
  • autocrine motility factor receptor (CpipJ_CPIJ016043) antibody
  • autocrine motility factor receptor amfr (Smp_150210.2) antibody
  • autocrine motility factor receptor amfr (Smp_047420) antibody
  • autocrine motility factor receptor (amfr) antibody
  • autocrine motility factor receptor (Amfr) antibody
  • autocrine motility factor receptor, E3 ubiquitin protein ligase (Amfr) antibody
  • GP78 antibody
  • RNF45 antibody
  • wu:fi06e06 antibody
  • wu:fi37e05 antibody
  • zgc:63893 antibody

Protein level used designations for AMFR

autocrine motility factor receptor , autocrine motility factor receptor, amfr , autocrine motility factor receptor amfr , autocrine motility factor receptor, isoform 2-like , AMF receptor , E3 ubiquitin-protein ligase AMFR , RING finger protein 45

GENE ID SPECIES
415697 Gallus gallus
549837 Xenopus (Silurana) tropicalis
735643 Pan troglodytes
5567121 Aedes aegypti
6049686 Culex quinquefasciatus
8346192 Schistosoma mansoni
8348102 Schistosoma mansoni
100392285 Callithrix jacchus
100476438 Ailuropoda melanoleuca
100601377 Nomascus leucogenys
406442 Danio rerio
507541 Bos taurus
23802 Mus musculus
398777 Xenopus laevis
267 Homo sapiens
487269 Canis lupus familiaris
361367 Rattus norvegicus
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