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anti-BCL2-Associated Athanogene 2 (BAG2) Antibodies

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Additionally we are shipping BAG2 Proteins (13) and BAG2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAG2 9532 O95816
BAG2 213539 Q91YN9
BAG2 690038  
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Top anti-BAG2 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB BAG2 Antibody (C-term) (ABIN657974) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the BAG2 antibody detected the BAG2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-BAG2 Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184625 (0.3µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB BAG2 monoclonal antibody (M01), clone 6E12 Western Blot analysis of BAG2 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Anti-BAG2 antibody, Western blotting Lane 1: Rat Testis Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: A549 Cell Lysate Lane 4: A431 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- BAG2 Picoband antibody,IHC(P) IHC(P): Rat Testis Tissue Anti- BAG2 Picoband antibody,IHC(P) IHC(P): Mouse Testis Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded U87 xenograft, using BAG2, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: A431 B: HeLa 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

BAG2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-BAG2 Antibodies

  1. Human Monoclonal BAG2 Primary Antibody for WB - ABIN394729 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)
    Show all 5 references for ABIN394729

  2. Human Polyclonal BAG2 Primary Antibody for IHC (p), WB - ABIN657974 : Arndt, Daniel, Nastainczyk, Alberti, Höhfeld: BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. in Molecular biology of the cell 2005 (PubMed)
    Show all 3 references for ABIN657974

  3. Human Polyclonal BAG2 Primary Antibody for WB - ABIN374110 : Dai, Qian, Li, McDonough, Borchers, Huang, Takayama, Younger, Ren, Cyr, Patterson: Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against BAG2 Interaction Partners

Human BCL2-Associated Athanogene 2 (BAG2) interaction partners

  1. NF-kappaB (show NFKB1 Antibodies)-mediated modulation of BAG2 expression regulates the shift between the neurotrophic and neurotoxic effects of Abeta1-42.

  2. Thus, BAG2 promotes mutant p53 (show TP53 Antibodies) accumulation and gain-of-function in tumor growth, metastasis and chemoresistance.

  3. This study showed that BAG2 (Bcl-2 (show BCL2 Antibodies) associated athanogene family protein 2) and BAG5 (show BAG5 Antibodies) (Bcl-2 (show BCL2 Antibodies)-associated athanogene family protein 5 (show CAPS Antibodies)) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination

  4. we measured the binding of human Hsp72 (HSPA1A (show HSPA1A Antibodies)) to BAG1 (show BAG1 Antibodies), BAG2, BAG3 (show BAG3 Antibodies), and the unrelated NEF Hsp105 (show HSPH1 Antibodies). These studies revealed a clear hierarchy of affinities: BAG3 (show BAG3 Antibodies) > BAG1 (show BAG1 Antibodies) > Hsp105 (show HSPH1 Antibodies) >> BAG2.

  5. this data correlate BAG2 to PINK1 (show PINK1 Antibodies) for the first time, strengthening the important role of BAG2 in Parkinson disease -related neurodegeneration.

  6. BAG2 was directly phosphorylated at serine 20 in vitro by MAPKAPK2 (show MAPKAPK2 Antibodies) and MAPKAP2 is also required for phosphorylation of BAG2 in vivo.

  7. BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (show HSPBP1 Antibodies) (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIP

  8. The activity of BAG-2 resembles that of the previously characterized Hsc70 (show HSPA8 Antibodies) cochaperone and CHIP inhibitor HspBP1 (show HSPBP1 Antibodies).

Mouse (Murine) BCL2-Associated Athanogene 2 (BAG2) interaction partners

  1. findings support the notion that BAG2 is an upstream regulator of the PINK1 (show PINK1 Antibodies)/PARKIN (show PARK2 Antibodies) signaling pathway.

  2. Native Bag2-NTD crystals diffracted to 2.27 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 75.5, b = 84.7, c = 114.1 A

  3. Free and Hsc70 (show HSPA8 Antibodies)-bound crystal structures of Bag2-BNB show its dimeric structure, in which a flanking linker helix and loop bind to Hsc70 (show HSPA8 Antibodies) to promote nucleotide exchange.

BAG2 Antigen Profile

Protein Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene names and symbols associated with BAG2

  • BCL2-associated athanogene 2 (bag2) antibody
  • BCL2-associated athanogene 2 (BAG2) antibody
  • BCL2-associated athanogene 2 (LOC100346462) antibody
  • BCL-2-associated athanogene 2 (BAG2) antibody
  • BCL2-associated athanogene 2 (Bag2) antibody
  • Bcl2-associated athanogene 2 (Bag2) antibody
  • 2610042A13Rik antibody
  • ATBAG2 antibody
  • BAG-2 antibody
  • BAG2 antibody
  • BC016230 antibody
  • BCL-2-associated athanogene 2 antibody
  • dJ417I1.2 antibody
  • MGC89300 antibody
  • MTG10.13 antibody
  • MTG10_13 antibody
  • zgc:64195 antibody

Protein level used designations for BAG2

BCL2-associated athanogene 2 , BAG family molecular chaperone regulator 2 , putative BCL2-associated athanogene 2 , BAG-family molecular chaperone regulator-2 , bcl-2-associated athanogene 2 , dJ417I1.2 (BAG-family molecular chaperone regulator 2) , BAG-2

GENE ID SPECIES
448388 Xenopus (Silurana) tropicalis
462797 Pan troglodytes
100346462 Oryctolagus cuniculus
100190641 Taeniopygia guttata
836330 Arabidopsis thaliana
9532 Homo sapiens
393975 Danio rerio
421880 Gallus gallus
610506 Canis lupus familiaris
506107 Bos taurus
213539 Mus musculus
690038 Rattus norvegicus
Selected quality suppliers for anti-BAG2 (BAG2) Antibodies
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