BAG2 Products
(BCL2-Associated Athanogene 2 (BAG2))
Categories
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
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Featured BAG2 Categories
BAG2 Antibodies
High quality antibodies with extensive validation data.
BAG2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BAG2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN2775278
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7145213
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN657974
Quantity
400 μL
Datasheet
Datasheet
Recommended BAG2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121981
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346362
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346364
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BAG2 products
: "Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia." in: Cell death & disease, Vol. 10, Issue 10, pp. 730, (2019) (PubMed).: "GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis." in: Journal of cellular biochemistry, Vol. 117, Issue 8, pp. 1813-21, (2016) (PubMed).
: "JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4684-97, (2016) (PubMed).
: "BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function." in: eLife, Vol. 4, (2015) (PubMed).
: "Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry." in: The American journal of pathology, Vol. 174, Issue 2, pp. 361-70, (2009) (PubMed).
: "Regulation of the cytoplasmic quality control protein degradation pathway by BAG2." in: The Journal of biological chemistry, Vol. 280, Issue 46, pp. 38673-81, (2005) (PubMed).
Synonyms and alternative names related to BAG2
BCL2 associated athanogene 2 (bag2), BCL2 associated athanogene 2 (BAG2), BCL-2-associated athanogene 2 (BAG2), BCL2-associated athanogene 2 (bag2), BCL2-associated athanogene 2 (Bag2), Bcl2-associated athanogene 2 (Bag2), 2610042A13Rik, ATBAG2, BAG-2, bag2, BAG2, BC016230, BCL-2-associated athanogene 2, dJ417I1.2, MGC89300, MTG10.13, MTG10_13, zgc:64195Protein level used designations for BAG2
- BCL2-associated athanogene 2
- BAG family molecular chaperone regulator 2
- putative BCL2-associated athanogene 2
- BAG-family molecular chaperone regulator-2
- bcl-2-associated athanogene 2
- dJ417I1.2 (BAG-family molecular chaperone regulator 2)
- BAG-2
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