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BCL6 Co-Repressor Proteins (BCOR)

The protein encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. Additionally we are shipping BCOR Antibodies (53) and BCOR Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat BCOR BCOR 317346  
BCOR 54880 Q6W2J9
Mouse BCOR BCOR 71458 Q8CGN4
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Top BCOR Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BCOR Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for BCL6 Co-Repressor (BCOR) Interaction Partners

Human BCL6 Co-Repressor (BCOR) interaction partners

  1. Data suggest the detection of the partial duplication inside exon 15 of proto-oncogene (show RAB1A Proteins) protein BCOR as part of the diagnostic process of pediatric kidney tumors.

  2. Report mutually exclusive BCOR internal tandem duplications and YWHAE (show YWHAE Proteins)-NUTM2 fusions in clear cell sarcoma of kidney.

  3. The present study further expands the genetic spectrum of small blue round cell tumors, with 2 novel fusions, BCOR-MAML3 and ZC3H7B-BCOR, identified

  4. Somatic internal tandem duplications (ITDs) clustering in the C terminus of BCOR were found in 85% of pediatric clear cell sarcoma of the kidney. Mutant BCOR transcripts and proteins are markedly upregulated in ITD-positive tumours.

  5. This study adds to recent reports on the clinicopathologic spectrum of BCOR-CCNB3 (show CCNB3 Proteins) fusion-positive sarcomas, a newly emerging entity within the undifferentiated unclassified sarcoma category

  6. Using reported human BCOR mutations in patients with oculofaciocardiodental syndrome, the authors identified nuclear localization signals at two possible sites; at aa1131-1141 (NLS1) and at aa1158-1167(NLS2).

  7. study concluded that in pediatric acute myeloid leukemia, BCOR and BCORL1 mutations rarely occur

  8. Data indicate that the internal tandem duplications in the BCOR gene (BCL6 corepressor) affecting the C terminus in 100% (20/20) of clear cell sarcoma of the kidney (CCSK) tumors

  9. report of the clinical and molecular data of 3 new patients with oculofaciocardiodenta and review the literature for all published patients and their mutations in the BCOR gene

  10. findings identify the BCL6 (show BCL6 Proteins)/BCOR/SIRT1 (show SIRT1 Proteins) complex as a potent repressor of the SHH (show SHH Proteins) pathway in normal and oncogenic neural development

Mouse (Murine) BCL6 Co-Repressor (BCOR) interaction partners

  1. Data show that BCL6 interacting corepressor Bcor Is Specifically Down-regulated by Activin Signaling in trophoblast stem cells (TSCs).

  2. T cell-expressed BCOR is critical for optimal GC-Tfh cell differentiation and humoral immunity.

  3. IRF8 (show IRF8 Proteins) pairs with BCL6 co-repressor BCOR in the nucleus to enhance its transcriptional repressive activity.

  4. Results suggest that Bcor expressed in the mesenchyme plays crucial roles during early tooth development.

  5. Study isolated an Fbxl10/Jhdm1B (show KDM2B Proteins) complex by Study using a high throughput proteomics approach identified interactors with Rnf2 (show RNF2 Proteins) including Fbxl10/Jhdm1B (show KDM2B Proteins), casein kinase subunits, and the BcoR corepressor

  6. Bcor plays a role in differentiation of multiple tissue lineages during early embryonic development.

BCOR Protein Profile

Protein Summary

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.

Gene names and symbols associated with BCL6 Co-Repressor Proteins (BCOR)

  • BCL6 co-repressor (bcor)
  • BCL6 co-repressor (BCOR)
  • BCL6 co-repressor (Bcor)
  • BCL6 corepressor (BCOR)
  • BCL6 interacting corepressor (Bcor)
  • 5830466J11Rik protein
  • 8430401K06Rik protein
  • ANOP2 protein
  • BCOR protein
  • BcorR protein
  • D930024N20Rik protein
  • MAA2 protein
  • MCOPS2 protein
  • mKIAA1575 protein
  • RGD1562735 protein

Protein level used designations for BCL6 Co-Repressor Proteins (BCOR)

BCL-6 corepressor , BCL6 co-repressor , BCL-6 interacting corepressor , Bcl6 interacting corepressor

GENE ID SPECIES
402921 Danio rerio
418574 Gallus gallus
465574 Pan troglodytes
541088 Bos taurus
698644 Macaca mulatta
100050335 Equus caballus
317346 Rattus norvegicus
784529 Bos taurus
54880 Homo sapiens
480880 Canis lupus familiaris
71458 Mus musculus
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