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BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) ELISA Kits

The protein encoded by BAP1 localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). Additionally we are shipping BAP1 Antibodies (124) and BAP1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse BAP1 BAP1 104416 Q99PU7
Anti-Human BAP1 BAP1 8314 Q92560
BAP1 306257 D3ZHS6
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Top BAP1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 0.094 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$540.00
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Cow
96 Tests Log in to see 15 to 18 Days
$1,029.60
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Chicken
96 Tests Log in to see 15 to 18 Days
$1,095.60
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More ELISA Kits for BAP1 Interaction Partners

Mouse (Murine) BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. the interaction between nephrin and MAGI-1 regulates Rap1 activation in podocytes to maintain long term slit diaphragm structure

  2. BAP1(+/-) mice exposed to low-dose asbestos fibers showed an altered peritoneal inflammatory response and higher levels of pro-tumorigenic alternatively polarized M2 macrophages, and lower cytokine levels. They had a higher incidence of mesothelioma.

  3. Bap1 loss led to a fully penetrant myeloproliferative disease with splenomegaly, leukocytosis, anemia and progenitor expansion via alterations in histone methylation and gene expression.

  4. INO80 (show INO80 ELISA Kits) is stabilized and targeted to replication forks by BAP1 during normal DNA synthesis but downregulated in BAP1 defective cancer cells

  5. Both Vhl (show VHL ELISA Kits) and Bap1 are required for kidney function. Inactivation of Bap1 in neprhon progenitor cells causes renal failure earlier than Vhl (show VHL ELISA Kits) inactivation. Bap1 is also a stronger tumor suppressor gene than Vhl (show VHL ELISA Kits) in the kidney.

  6. Drawing parallels to human disease, these unbiased genetic findings indicate that BAP1 mutation carriers are predisposed to the tumorigenic effects of asbestos and suggest that high penetrance of mesothelioma requires such environmental exposure.

  7. Cx32 (show GJB1 ELISA Kits) expression is in part related to induction of tight junctions through modulation of Magi1 (show CNKSR3 ELISA Kits) expression in an immortalized hepatic cell line.

  8. ARIP1 (show MAGI2 ELISA Kits) and ARIP2 (show SYNJ2BP ELISA Kits) are co-expressed in some nerve cells and their biological activities are distinct.

  9. results identify a potent tumor suppressor function for BAP1 in myeloid neoplasia; propose that BAP1 forms a core complex with HCF-1 (show HCFC1 ELISA Kits) and OGT (show OGT ELISA Kits) that can differentially recruit additional histone-modifying enzymes to regulate gene expression and preserve norm

  10. Data conclude that the up-regulation of sdk-1 (show SDK1 ELISA Kits) in podocytes is an important pathogenic factor in glomerulosclerosis and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 (show CNKSR3 ELISA Kits) function.

Human BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. on the basis of our meta-analysis, we have demonstrated a peculiar role of BAP1 (show RNF2 ELISA Kits) in influencing the prognosis in cancer. Thus, BAP1 (show RNF2 ELISA Kits) could be considered as an important potential target for personalized medicine.

  2. Patients with uveal melanoma can be classified into 3 groups, of which EIF1AX (show EIF1AX ELISA Kits)-mutated tumors and tumors without BAP1 (show RNF2 ELISA Kits), SF3B1, or EIF1AX (show EIF1AX ELISA Kits) mutations are associated with prolonged survival and low metastatic risk, SF3B1-mutated tumors are associated with late metastasis

  3. The frequency of BAP1 (show RNF2 ELISA Kits) germline pathogenic variants in consecutive Finnish patients with uveal melanoma who come from a high-risk region for the development of this cancer is comparable with reports from other populations.

  4. BAP1 (show RNF2 ELISA Kits), SF3B1, and EIF1AX (show EIF1AX ELISA Kits) mutations occur during uveal melanoma tumor progression in an almost mutually exclusive manner and are associated with different levels of metastatic risk.

  5. Our cohort included 257 lung cancer patients, of which 155 (60%) were adenocarcinomas and 72 (28%) were squamous cell carcinomas, with no other subtype comprising more than 3%. BAP1 (show RNF2 ELISA Kits) loss of expression was found in only one lung cancer. We conclude that BAP1 (show RNF2 ELISA Kits) mutation occurs very infrequently (0.4%) in non-small cell lung cancer.

  6. expression of BAP1 (show RNF2 ELISA Kits) is downregulated in gastric adenocarcinoma and its decreased expression is associated with more advanced tumor progressions (advanced T category, M category, and TNM (show ODZ1 ELISA Kits) stage) and malignant phenotypes (histologic grade). Additionally, low BAP1 (show RNF2 ELISA Kits) expression is correlated to poor prognosis in gastric adenocarcinoma.

  7. FISH analysis of the p16/CDKN2A status and BAP1 immunohistochemistry in the spindled mesothelium provide a more objective means to differentiate between biphasic mesothelioma and epithelioid mesothelioma with atypical stromal cells

  8. BAP1 (show RNF2 ELISA Kits) mutation is associated with melanocytic tumors of the central nervous system.

  9. Data showed that patients with biallelic BAP1 (show RNF2 ELISA Kits) mutation had the worse recurrence-free survival.

  10. BAP1 (show RNF2 ELISA Kits) mutations responsible for tumor predisposition syndrome were reported in 2 families.

BAP1 Antigen Profile

Antigen Summary

The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene.

Gene names and symbols associated with BAP1

  • Brca1 associated protein 1 (Bap1) antibody
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1) antibody
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (Bap1) antibody
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (bap1) antibody
  • membrane associated guanylate kinase, WW and PDZ domain containing 1 (Magi1) antibody
  • 2300006C11Rik antibody
  • AA989761 antibody
  • AIP3 antibody
  • AW553466 antibody
  • Baiap1 antibody
  • BAIAP3 antibody
  • BAP1 antibody
  • Gukmi1 antibody
  • hucep-6 antibody
  • hucep-13 antibody
  • Magi-1 antibody
  • MAGI1c antibody
  • mKIAA0272 antibody
  • mKIAA4129 antibody
  • si:dkey-42i9.9 antibody
  • TNRC19 antibody
  • uch-x4 antibody
  • uchl2 antibody
  • WWP3 antibody

Protein level used designations for BAP1

BRCA1-associated protein 1 , ubiquitin C-terminal hydrolase X4 , ubiquitin carboxyl-terminal hydrolase BAP1 , cerebral protein 6 , cerebral protein-13 , Brca1 associated protein 1 , BAI1-associated protein 3 , ubiquitin carboxy-terminal hydrolase , BAI1-associated protein 1 , BAP-1 , guanylate kinase membrane-associated inverted 1 , membrane-associated guanylate kinase inverted 1 , membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

GENE ID SPECIES
104416 Mus musculus
8314 Homo sapiens
484737 Canis lupus familiaris
306257 Rattus norvegicus
100124510 Bos taurus
415944 Gallus gallus
558885 Danio rerio
734438 Xenopus laevis
14924 Mus musculus
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