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BHLHB9 is a member of a gene family which encodes proteins with a basic helix-loop-helix domain. Additionally we are shipping BHLHB9 Antibodies (15) and many more products for this protein.
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Report that some regions of p60TRP were more prone to specific mutations, with two hotspots for mutations at E15 and E171.
Down-regulation in the brain of Alzheimer's disease subjects point to a possible pivotal role of p60TRP in the control of cellular aging and survival.
Our data suggests that in vivo overexpression of neuronal p60TRP significantly affects cognitive and neuroprotective capacities.
in vivo neural over-expression of transgenic p60TRP with its neuroprotective therapeutic potential significantly affects cardiovascular capacities.
This gene is a member of a gene family which encodes proteins with a basic helix-loop-helix domain. Other members of this gene family encode proteins which function as transcription factors, either enhancing or inhibiting transcription depending on the activity of other DNA binding proteins. The coding region of this gene is located entirely within the terminal exon. The encoded protein may be involved in the survival of neurons (PMID: 15034937). Multiple alternatively spliced variants, encoding the same protein, have been identified.
, protein BHLHb9
, transcription regulator of 60 kDa