Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010].. Additionally we are shipping Beclin 1 Kits (40) and Beclin 1 Proteins (19) and many more products for this protein.
Showing 10 out of 448 products:
Dog (Canine) Polyclonal Beclin 1 Primary Antibody for ICC, IF - ABIN259945
Liang, Kleeman, Jiang, Gordon, Goldman, Berry, Herman, Levine: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. in Journal of virology 1998
Show all 29 references for ABIN259945
Human Monoclonal Beclin 1 Primary Antibody for IHC, IHC (p) - ABIN314194
Ko, Lin, Flomenberg, Pestell, Howell, Sotgia, Lisanti, Martinez-Outschoorn: Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance. in Cancer biology & therapy 2012
Show all 16 references for ABIN314194
Human Polyclonal Beclin 1 Primary Antibody for IHC (p), WB - ABIN388545
Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005
Show all 10 references for ABIN388545
Human Polyclonal Beclin 1 Primary Antibody for FACS, IHC (p) - ABIN388546
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005
Show all 10 references for ABIN388546
Human Monoclonal Beclin 1 Primary Antibody for IF, IHC (p) - ABIN387797
Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010
Show all 9 references for ABIN387797
Human Polyclonal Beclin 1 Primary Antibody for EIA, IF - ABIN497977
Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004
Show all 6 references for ABIN497977
Chicken Monoclonal Beclin 1 Primary Antibody for IHC (p), IHC - ABIN314193
Botbol, Patel, Macian: Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. in Autophagy 2015
Show all 2 references for ABIN314193
Human Monoclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN1449374
Starr, Child, Wehrly, Hansen, Hwang, López-Otin, Virgin, Celli: Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. in Cell host & microbe 2012
Show all 2 references for ABIN1449374
Human Polyclonal Beclin 1 Primary Antibody for WB - ABIN658010
Oberstein, Jeffrey, Shi: Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. in The Journal of biological chemistry 2007
Chicken Monoclonal Beclin 1 Primary Antibody for IHC, WB - ABIN314196
Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. in Nature communications 2015
Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.
Nuclear Beclin1 overexpression is associated with colorectal cancer.
Beclin-1 acts as a tumor suppressor by regulating the hedgehog (show SHH Antibodies) (HH) signaling pathway through Gli2 (show GLI2 Antibodies) expression in gastric adenocarcinoma.
Results show that the expression of AMBRA1 (show AMBRA1 Antibodies) and Beclin-1 is increased in human gastric adenocarcinoma (GC) tissues. High protein expression of AMBRA1 (show AMBRA1 Antibodies) and Beclin-1 is correlated with tumor invasion and is an independent poor prognostic marker in GC patients.
These results demonstrate that Beclin1 acts as a tumour suppressor in the development or progression of OTSCC and that Beclin1 may represent a novel prognostic marker for patients with OTSCC.
the overexpression of Beclin 1 promoted apoptosis and decreased invasion by upregulating the expression of ECRG4 (show C2orf40 Antibodies) in A549 lung adenocarcinoma cells. Therefore, the selection of Beclin l as a target for gene therapy represents a more effective method for the treatment of lung cancer.
PVT1 overexpression increased the expression of Atg7 (show ATG7 Antibodies) and Beclin1 by targeting miR (show MLXIP Antibodies)-186, which induced protective autophagy, thus promoting glioma vascular endothelial cell proliferation, migration, and angiogenesis. Therefore, PVT1 and miR (show MLXIP Antibodies)-186 can provide new therapeutic targets for future anti-angiogenic treatment of glioma
our study further confirms that Beclin1- and reactive oxygen species-dependent autophagy induced by ABT-737 also plays a protective function in HepG2/ADM (show ADM Antibodies) cells, which show B-cell lymphoma 2 expression higher than that in HepG2 cells.
miR-17-5p plays an important role in radiosensitivity of glioma cells by inhibiting beclin-1-mediated autophagy. Targeting miR-17-5p/beclin-1/autophagy pathway may be a promising strategy to enhance the efficacy of radiotherapy in glioma.
Low expression of BECN1 is associated with lymph node metastasis in gastric cancer.
High Beclin-1 expression (alone or in combination with SIRT1 (show SIRT1 Antibodies)) predicted shorter overall survival and relapse-free survival in gastric cancer.
this study shows that knockdown of beclin1 enhances macrophage-associated (show CD163 Antibodies) phagocytosis and intracellular killing of Pseudomonas aeruginosa
provide the novel evidence that GADD45A (show GADD45A Antibodies) inhibits autophagy via impairing the BECN1-PIK3C3 (show PIK3C3 Antibodies) complex formation
in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.
suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling
FBG1 (show FBXO2 Antibodies) degrades A1AT (show SERPINA1 Antibodies)-Z through a Beclin1-dependent arm of autophagy.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (show UVRAG Antibodies)-VPS34 (show PIK3C3 Antibodies) complex.
a mechanism of inverse coregulation between BECN1 and MCL1 (show MCL1 Antibodies) significantly contributes to their opposing roles in tumorigenesis
FKBP5 (show FKBP5 Antibodies) associates with BECN1, changes its phosphorylation and protein levels and enhances markers of autophagy and autophagic flux
identifies a novel negative regulator of autophagy and suggests that RNF216 (show RNF216 Antibodies) may be a target for treatment of inflammatory diseases
Inverse co-regulation of Beclin 1 and Mcl-1 (show MCL1 Antibodies) represents a mechanism of functional counteraction in cancer.
Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR (show FRAP1 Antibodies), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.
Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009
beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)
, beclin 1
, beclin 1 proteinBeclin-1-like protein
, myosin-like BCL2 interacting protein
, ATG6 autophagy related 6 homolog
, beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)
, beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
, coiled-coil myosin-like BCL2-interacting protein
, Bcl-2-interacting protein beclin
, coiled-coil, myosin-like BCL2-interacting protein
, beclin 1 (coiled-coil, myosin-like BCL2-interacting protein)
, autophagy-related protein 6