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Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 Proteins (BLOC1S1)

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. Additionally we are shipping BLOC1S1 Antibodies (17) and BLOC1S1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BLOC1S1 2647 P78537
BLOC1S1 288785 D3ZKU7
BLOC1S1 14533 O55102
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Top BLOC1S1 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) (AA 1-153), (full length) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,253.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,253.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,253.17
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,337.50
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,339.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BLOC1S1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced BLOC1S1 Proteins

  1. Human BLOC1S1 Protein expressed in Escherichia coli (E. coli) - ABIN1046616 : Inoue, Isomura, Ikegawa, Fujiwara, Shin, Moriya, Nakamura: Isolation and characterization of a human cDNA clone (GCN5L1) homologous to GCN5, a yeast transcription activator. in Cytogenetics and cell genetics 1996 (PubMed)
    Show all 2 references for ABIN1046616

More Proteins for Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaction Partners

Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) interaction partners

  1. The mitochondrial acetylation status controlled by Sirt3 (show SIRT3 Proteins) and its proposed opponent GCN5L1 is an important regulator of the metabolic adaptation of mitochondrial translation.

  2. Using cancer cell lines, the study shows that BLOC1S1 mRNA is specifically cleaved by IRE1 (show ERN1 Proteins) at guanine 444, but only under conditions of IRE1 (show ERN1 Proteins) hyperactivation.

  3. The Hermansky-Pudlak syndrome complex BLOC-1 and its cargo PI4KIIalpha interact with regulators of the actin cytoskeleton.

  4. BLOS1 interacts with KXD1.

  5. GCN5L1/BLOC1S1 regulates lysine acetylation in mitochondria.

  6. Quantitative proteomic studies expand the functional repertoire of the BLOC-1 complex and provide insight into putative molecular pathways of schizophrenia susceptibility.

  7. Together this study data provide evidence for the involvement of the BLOC-1 protein complex in SZ pathogenesis.

  8. Experimental investigation of five specific genes, AP3B1 (show AP3B1 Proteins), ATP6AP1 (show ATP6AP1 Proteins), BLOC1S1, LAMP2 (show LAMP2 Proteins), and RAB11A (show RAB11A Proteins), has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

  9. Biogenesis of Lysosome-related Organelles co (show SNAPIN Proteins)mplex-1 (BLOC-1) subunit 1 (BLOS1).

Mouse (Murine) Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) interaction partners

  1. BLOS1 interacts with sorting nexin 2 (show SNX2 Proteins) and the ESCRT-I (show VPS28 Proteins) component TSG101 (show TSG101 Proteins) to mediate the sorting of EGFR (show EGFR Proteins) into endosomal compartments

  2. Here we show that genetic deletion of GCN5L1 has a direct positive effect on the expression and activity of Transcriptional Factor EB (TFEB (show TFEB Proteins)), which acts as a master regulator of autophagy.

  3. Mutations in the human genes encoding Snapin (show SNAPIN Proteins) and the BLOS proteins could underlie novel forms of Hermansky-Pudlak syndrome as seen in mouse models

  4. Defects in all the 5 known components of BLOC-1 (show PLDN Proteins), including RP, cause severe Hermansky Pudlak syndrome in mice, suggesting that the subunits are nonredundant and that BLOC-1 (show PLDN Proteins) plays a key role in organelle biogenesis.

  5. These results indicate that the BLOC-1 (show PLDN Proteins) and AP-3 (show AP3B1 Proteins) protein complexes affect the targeting of SNARE (show VTI1B Proteins) and non-SNARE (show VTI1B Proteins) AP-3 (show AP3B1 Proteins) cargoes and suggest a function of the BLOC-1 (show PLDN Proteins) complex in membrane protein sorting.

BLOC1S1 Protein Profile

Protein Summary

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004

Gene names and symbols associated with BLOC1S1

  • biogenesis of lysosomal organelles complex-1, subunit 1 (BLOC1S1)
  • biogenesis of lysosomal organelles complex-1, subunit 1 (Bloc1s1)
  • biogenesis of lysosome-related organelles complex-1, subunit 1 (Bloc1s1)
  • AI839753 protein
  • BLOS1 protein
  • Gcn5l1 protein
  • MICoA protein
  • RT14 protein

Protein level used designations for BLOC1S1

BLOC subunit 1 , BLOC-1 subunit 1 , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 , GCN5 general control of amino-acid synthesis 5-like 1 , GCN5-like protein 1 , MTA1-interacting coactivator , biogenesis of lysosome-related organelles complex 1 subunit 1 , biogenesis of lysosome-related organelles complex-1, subunit 1 , GCN5 general control of amino acid synthesis-like 1 , general control of amino acid synthesis, yeast homolog-like 1 , general control of amino acid synthesis-like 1

GENE ID SPECIES
2647 Homo sapiens
615149 Bos taurus
288785 Rattus norvegicus
100190807 Pongo abelii
14533 Mus musculus
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