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The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. Additionally we are shipping BCKDK Kits (21) and BCKDK Proteins (9) and many more products for this protein.
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Cow (Bovine) Polyclonal BCKDK Primary Antibody for WB - ABIN2784788
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
leucine supplementation increased the expression of enzymes (BCAT1 (show BCAT1 Antibodies), BCAT2 (show BCAT2 Antibodies) and BCKDK) that metabolize branched-chain amino acids.
Results suggest that targeting mitochondrial BCKD kinase (BDK) as a pharmacological approach to mitigate the branched-chain amino acids (BCAAs) accumulation in metabolic diseases and heart failure.
Results demonstrate that BCKDK mutations can result in neurobehavioral deficits in humans.
The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene.
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
, branched chain ketoacid dehydrogenase kinase
, 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial-like
, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial-like
, branched-chain alpha-ketoacid dehydrogenase kinase
, branched chain alpha-ketoacid dehydrogenase kinase
, branched chain keto acid dehydrogenase kinase