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anti-Bromodomain PHD Finger Transcription Factor (BPTF) Antibodies

BPTF was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BPTF 207165  
BPTF 303617  
BPTF 2186 Q12830
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Top anti-BPTF Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using BPTF mAb against HEK293 (1) and BPTF (AA: 503-670) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated DB   50 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-BPTF/FALZ Polyclonal Antibody, Unconjugated (ABIN1386560) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$991.83
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

BPTF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BPTF Antibodies

  1. Human Monoclonal BPTF Primary Antibody for ELISA, WB - ABIN968990 : Landry, Sharov, Piao, Sharova, Xiao, Southon, Matta, Tessarollo, Zhang, Ko, Kuehn, Yamaguchi, Wu: Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. in PLoS genetics 2008 (PubMed)
    Show all 2 references for ABIN968990

More Antibodies against BPTF Interaction Partners

Mouse (Murine) Bromodomain PHD Finger Transcription Factor (BPTF) interaction partners

  1. We find that the melanocyte stem cells from these animals are abnormal and that once they are stimulated at anagen, Bptf is required to ensure the expression of melanocyte markers and their differentiation into mature adult melanocytes.

  2. NURF regulation occurs partly through physical and functional interactions with the ubiquitous and multivalent factors Ctcf and cohesin

  3. Results suggest that BPTF/FAC1 is essential in the extraembryonic lineage for correct development of the ectoplacental cone and fetomaternal interactions.

  4. study concludes that Bptf likely regulates genes and signaling pathways essential for the development of key tissues of the early mouse embryo

Human Bromodomain PHD Finger Transcription Factor (BPTF) interaction partners

  1. somatic frameshift mutations of BPTF were present in gastric cancer and colorectal cancers

  2. BPTF plays an essential role in cell growth and survival by targeting multiply signaling pathways in human lung cancers

  3. High BPTF expression was significantly correlated with tumor progression and may be a potent prognostic marker of colorectal cancer.

  4. The PHD (show PDC Antibodies)-adjacent bromodomain in BPTF binds with marked selectivity H4K16ac, in combination with H3K4me3 at the mononucleosome level.

  5. the novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

  6. hkelch-like ECH (show NFE2L2 Antibodies)-associated protein 1 regulates FAC1 in addition to its known role in control of Nrf2 (show GABPA Antibodies)

  7. These findings suggest a role for FAC1 in apoptosis following release of Nrf2 (show GABPA Antibodies) from Keap1 (show KEAP1 Antibodies) in response to oxidative stress.

  8. crystallographic and NMR structures of the bromodomain-proximal PHD (show PDC Antibodies) finger of BPTF in free and H3(1-15)K4me3-bound states

  9. High FALZ expression is associated with metastatic spread to the brain in primary non-small cell lung cancer.

BPTF Antigen Profile

Protein Summary

This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely.

Gene names and symbols associated with BPTF

  • bromodomain PHD finger transcription factor (Bptf) antibody
  • bromodomain PHD finger transcription factor (BPTF) antibody
  • bromodomain PHD finger transcription factor (LOC100358904) antibody
  • bromodomain PHD finger transcription factor (bptf) antibody
  • fetal alzheimer antigen, falz (AaeL_AAEL015015) antibody
  • fetal alzheimer antigen, falz (AaeL_AAEL012607) antibody
  • fetal alzheimer antigen, falz (CpipJ_CPIJ011285) antibody
  • 9430093H17Rik antibody
  • BPTF antibody
  • FAC1 antibody
  • FALZ antibody
  • NURF301 antibody

Protein level used designations for BPTF

fetal Alzheimer antigen , nucleosome-remodeling factor subunit BPTF , bromodomain PHD finger transcription factor , nucleosome-remodeling factor subunit BPTF-like , fetal alzheimer antigen, falz , bromodomain and PHD domain transcription factor , bromodomain and PHD finger-containing transcription factor , fetal Alz-50 clone 1 protein , fetal Alz-50 reactive clone 1 , nucleosome remodeling factor, large subunit

GENE ID SPECIES
207165 Mus musculus
303617 Rattus norvegicus
454840 Pan troglodytes
480467 Canis lupus familiaris
532986 Bos taurus
100063881 Equus caballus
100079560 Ornithorhynchus anatinus
100358904 Oryctolagus cuniculus
100494204 Xenopus (Silurana) tropicalis
100525424 Sus scrofa
100594415 Nomascus leucogenys
5565968 Aedes aegypti
5576547 Aedes aegypti
6043987 Culex quinquefasciatus
2186 Homo sapiens
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