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anti-C-Type Lectin Domain Family 10, Member A (CLEC10A) Antibodies

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC10A Proteins (20) and CLEC10A Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLEC10A 10462 Q8IUN9
CLEC10A 17312 P49300
CLEC10A 64195  
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Top anti-CLEC10A Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB CLEC10A Antibody (N-term) flow cytometric analysis of MDA-MB435 cells ... CLEC10A Antibody (N-term) western blot analysis in MDA-MB435 cell line... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rat Biotin FACS   0.1 mg Log in to see 6 to 8 Days
$830.50
Details
Mouse Rat Un-conjugated Func, FACS, IHC (fro)   0.5 mg Log in to see 6 to 8 Days
$720.50
Details
Human Rabbit Un-conjugated FACS, WB CLEC10A Antibody (N-term)  western blot analysis in MDA-MB435 cell lin... CLEC10A Antibody (N-term)  flow cytometric analysis of MDA-MB435 cells... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat Un-conjugated FACS, IHC (fro)   0.25 mg Log in to see 6 to 8 Days
$467.50
Details
Mouse Rat PE FACS 100 μg Log in to see 10 to 12 Days
$326.12
Details
Mouse Rat APC FACS 100 μg Log in to see 10 to 12 Days
$342.43
Details
Mouse Rat Alexa Fluor 647 IF 100 μg Log in to see 10 to 12 Days
$353.29
Details
Mouse Rat PE-Cy7 FACS 100 μg Log in to see 10 to 12 Days
$380.47
Details
Mouse Rat PerCP-Cy5.5 ICFC 100 μg Log in to see 10 to 12 Days
$380.47
Details

CLEC10A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,
, ,
Rat (Rattus) ,

Top referenced anti-CLEC10A Antibodies

  1. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2658176 : Sakakura, Oo-Puthinan, Moriyama, Kimura, Moriya, Irimura, Shimada: Carbohydrate binding mechanism of the macrophage galactose-type C-type lectin 1 revealed by saturation transfer experiments. in The Journal of biological chemistry 2008 (PubMed)
    Show all 7 references for ABIN2658176

  2. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for IF - ABIN2657165 : Singh, Streng-Ouwehand, Litjens, Weelij, García-Vallejo, van Vliet, Saeland, van Kooyk: Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. in Molecular immunology 2009 (PubMed)
    Show all 7 references for ABIN2657165

  3. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2662591 : Tsuiji, Fujimori, Ohashi, Higashi, Onami, Hedrick, Irimura: Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. in The Journal of biological chemistry 2002 (PubMed)
    Show all 7 references for ABIN2662591

  4. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for ICFC - ABIN2660073 : Denda-Nagai, Aida, Saba, Suzuki, Moriyama, Oo-Puthinan, Tsuiji, Morikawa, Kumamoto, Sugiura, Kudo, Akimoto, Kawakami, Bovin, Irimura: Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 7 references for ABIN2660073

  5. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2659221 : Westcott, Delproposto, Geletka, Wang, Singer, Saltiel, Lumeng: MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. in The Journal of experimental medicine 2009 (PubMed)
    Show all 7 references for ABIN2659221

  6. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN181063 : Lederle, Hartenstein, Meides, Kunzelmann, Werb, Angel, Mueller: MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma. in Carcinogenesis 2010 (PubMed)
    Show all 3 references for ABIN181063

  7. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for Func, FACS - ABIN181064 : Leenen, de Bruijn, Voerman, Campbell, van Ewijk: Markers of mouse macrophage development detected by monoclonal antibodies. in Journal of immunological methods 1994 (PubMed)
    Show all 3 references for ABIN181064

  8. Human Polyclonal CLEC10A Primary Antibody for EIA, FACS - ABIN951291 : Adéchian, Giardina, Rémond, Papet, Buonocore, Gaudichon, Dardevet, Marzatico, Mosoni: Excessive energy intake does not modify fed-state tissue protein synthesis rates in adult rats. in Obesity (Silver Spring, Md.) 2009 (PubMed)
    Show all 2 references for ABIN951291

More Antibodies against CLEC10A Interaction Partners

Human C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. BRAF (show BRAF Antibodies)(V600E) mutation induces MGL ligand expression, thereby providing a direct link between oncogenic transformation and aberrant expression of immunosuppressive glycans in colorectal neoplasms.

  2. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

  3. expression of GalNAc moieties mirrors the T cell activation status, and thus only highly stimulated T cells are prone to the suppressive action of MGL.

  4. MGL triggering synergized with TLR2 (show TLR2 Antibodies)-induced pathways, leading to elevated IL-10 (show IL10 Antibodies) mRNA levels & enhanced TNF-alpha (show TNF Antibodies) mRNA stability. It promoted phosphorylation of the ERK (show EPHB2 Antibodies) & CREB (show CREB1 Antibodies), fine-tuning the DC maturation phenotype.

  5. Described is the use of recombinant CLEC10A (CD301), a human glycoreceptor of the C-type lectin (show MBL2 Antibodies) family, for the detection of ligands in sections from formalin-fixed, paraffin-embedded normal and cancerous mammary tissues.

  6. MGL engagement improved DC performance as antigen-presenting cells, promoting the upregulation of maturation markers, a decrease in phagocytosis, an enhancement of motility, and most importantly an increase in antigen-specific CD8 (show CD8A Antibodies)(+) T-cell activation.

Mouse (Murine) C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia

  2. Mgl1 (show LLGL1 Antibodies)-deficient mice displayed accelerated colonic propulsion and were hypersensitive to mu receptor-mediated inhibition of colonic motility.

  3. MGL1 (show LLGL1 Antibodies) is involved in T. crassiceps recognition and subsequent innate immune activation and resistance.

  4. The MGL1 (show LLGL1 Antibodies) functions as an attachment and entry receptor for influenza A virus.

  5. Syk (show SYK Antibodies) was involved in the CLR (show CALCR Antibodies)-mediated activation of mast cells by BP

  6. Hoxc8 (show HOXC8 Antibodies) downregulates Mgl1 (show LLGL1 Antibodies) tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  7. The authors conclude that lectin-mediated interactions of influenza virus with the MMR (show MRC1 Antibodies) or the MGL are required for the endocytic uptake of the virus into macrophages.

  8. mMGL1 preferentially binds Lewis X (show FUT4 Antibodies)-conjugated soluble polyacrylamides

  9. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.

  10. sialoadhesin (show SIGLEC1 Antibodies) acts as an endogenous counter-receptor for MGL1 (show LLGL1 Antibodies)

CLEC10A Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with CLEC10A

  • C-type lectin domain family 10, member A (CLEC10A) antibody
  • C-type lectin domain family 10, member A (Clec10a) antibody
  • CD301 antibody
  • CD301a antibody
  • CLEC10A antibody
  • CLECSF13 antibody
  • CLECSF14 antibody
  • HML antibody
  • HML2 antibody
  • M-ASGP-BP-1 antibody
  • Mgl antibody
  • Mgl1 antibody
  • Mgll antibody

Protein level used designations for CLEC10A

C-type lectin domain family 10, member A , C-type lectin, superfamily member 14 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived) , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) , C-type lectin domain family 10 member A , macrophage lectin 2 (calcium dependent) , macrophage asialoglycoprotein-binding protein 1 , macrophage galactose N-acetyl-galactosamine specific lectin 1 , Gal/GalNAc-specific lectin , M-ASGP-BP , M-ASGP-BP-1 , MMGL , macrophage galactose/N-acetylgalactosamine-specific lectin , monoglyceride lipase

GENE ID SPECIES
607405 Canis lupus familiaris
748824 Pan troglodytes
10462 Homo sapiens
17312 Mus musculus
64195 Rattus norvegicus
Selected quality suppliers for anti-CLEC10A (CLEC10A) Antibodies
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